1. Metabolic Enzyme/Protease
  2. Lipoxygenase
  3. EP6

EP6 is a potent 5-Lipoxygenase (5-LO) inhibitor. EP6 inhibits the cell viability of tumor cells without mutagenic activity. EP6 can be used in research of cancer.

For research use only. We do not sell to patients.

EP6 Chemical Structure

EP6 Chemical Structure

CAS No. : 1353567-32-4

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Description

EP6 is a potent 5-Lipoxygenase (5-LO) inhibitor. EP6 inhibits the cell viability of tumor cells without mutagenic activity. EP6 can be used in research of cancer[1].

IC50 & Target[1]

5-Lipoxygenase

0.05 μM (IC50)

In Vitro

EP6 suppresses 5-LO activity in intact polymorphonuclear leukocytes with an IC50 value of 0.16 μM and exhibits full inhibitory potency in cell free assays (IC50 value of 0.05 μM for purified 5-LO)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

390.52

Formula

C24H30N4O

CAS No.
SMILES

CC1=CN2C(C=C1)=NC(C3=CC=C(C=C3)N4CCOCC4)=C2NC5CCCCC5

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
EP6
Cat. No.:
HY-120495
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