2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. GABA Receptor iGluR
  4. Epiallopregnanolone

Epiallopregnanolone  (Synonyms: 5α,3β-THDOC)

Cat. No.: HY-124463
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Epiallopregnanolone (5α,3β-THDOC), a 3β-hydroxy neurosteroid, an antagonist at GABAA receptors and a NMDA receptor enhancer.

For research use only. We do not sell to patients.

Epiallopregnanolone Chemical Structure

Epiallopregnanolone Chemical Structure

CAS No. : 567-01-1

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Epiallopregnanolone Related Antibodies

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Description

Epiallopregnanolone (5α,3β-THDOC), a 3β-hydroxy neurosteroid, an antagonist at GABAA receptors and a NMDA receptor enhancer[1].

In Vivo

Epiallopregnanolone (5α,3β-THDOC; 1-100 mg/kg; ip) inhibits seizures induced by Pilocarpine in mice (ED50 of 45.9 mg/kg)[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Swiss mice (25-30 g) injected with Pilocarpine[2]
Dosage: 1-100 mg/kg
Administration: ip; once
Result: Inhibited seizures induced by Pilocarpine.
Molecular Weight

334.49

Formula

C21H34O3
CAS No.
SMILES

C[C@]12[C@]([H])([C@@]3(CC[C@]4(C[C@H](CC[C@@]4([C@]3(CC2)[H])C)O)[H])[H])CC[C@@H]1C(CO)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
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Epiallopregnanolone Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Epiallopregnanolone567-01-15α,3β-THDOCGABA ReceptoriGluRGamma-aminobutyric acid Receptorγ-Aminobutyric acid ReceptorIonotropic glutamate receptorsGABAA receptor3β-hydroxy neurosteroidNMDA receptorInhibitorinhibitorinhibit

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