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Etanidazole  (Synonyms: SR 2508)

Cat. No.: HY-116972 Purity: 99.86%
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Etanidazole (SR 2508), a 2-nitroimidazole compound, is a hypoxic radiosensitizer used in cancer diagnosis and chemotherapy research.

For research use only. We do not sell to patients.

Etanidazole Chemical Structure

Etanidazole Chemical Structure

CAS No. : 22668-01-5

Size Price Stock Quantity
5 mg USD 180 In-stock
10 mg USD 290 In-stock
25 mg USD 560 In-stock
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Based on 1 publication(s) in Google Scholar

Etanidazole Related Antibodies

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Description

Etanidazole (SR 2508), a 2-nitroimidazole compound, is a hypoxic radiosensitizer used in cancer diagnosis and chemotherapy research[1].

Cellular Effect
Cell Line Type Value Description References
HCT-116 IC50
1 mM
Compound: 2
Cytotoxicity against human HCT116 cells incubated for 4 hrs under anaerobic condition measured after 5 days by sulforhodamine B assay
Cytotoxicity against human HCT116 cells incubated for 4 hrs under anaerobic condition measured after 5 days by sulforhodamine B assay
[PMID: 29253343]
Vero CC50
> 16 μg/mL
Compound: Etanidazole
Cytotoxicity against african green monkey Vero cells after 72 hrs by CellTiterGlo assay
Cytotoxicity against african green monkey Vero cells after 72 hrs by CellTiterGlo assay
[PMID: 22691154]
Molecular Weight

214.18

Formula

C7H10N4O4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(CN1C=CN=C1[N+]([O-])=O)NCCO
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 8.33 mg/mL (38.89 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.6690 mL 23.3449 mL 46.6897 mL
5 mM 0.9338 mL 4.6690 mL 9.3379 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

×
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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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(per animal)

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 4.6690 mL 23.3449 mL 46.6897 mL 116.7243 mL
5 mM 0.9338 mL 4.6690 mL 9.3379 mL 23.3449 mL
10 mM 0.4669 mL 2.3345 mL 4.6690 mL 11.6724 mL
15 mM 0.3113 mL 1.5563 mL 3.1126 mL 7.7816 mL
20 mM 0.2334 mL 1.1672 mL 2.3345 mL 5.8362 mL
25 mM 0.1868 mL 0.9338 mL 1.8676 mL 4.6690 mL
30 mM 0.1556 mL 0.7782 mL 1.5563 mL 3.8908 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Etanidazole Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Etanidazole22668-01-5SR 2508SR2508SR-2508Othershypoxicradiosensitizercancer diagnosischemotherapyInhibitorinhibitorinhibit

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