2. Metabolic Enzyme/Protease
  3. FABP
  4. FABP4-IN-4

FABP4-IN-4 (Compound 30) is an orally active inhibitor for FABP, with IC50 of 1.18 μM for FABP 1. FABP4-IN-4 improves the glucose tolerance, reduces the level of blood glucose, plasma lipids and hepatic inflammatory factors, attenuates hepatic steatosis, and exhibits anti-inflammatory effects in mouse diet-induced obesity models.

For research use only. We do not sell to patients.

FABP4-IN-4 Chemical Structure

FABP4-IN-4 Chemical Structure

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FABP4-IN-4 Related Antibodies

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Description

FABP4-IN-4 (Compound 30) is an orally active inhibitor for FABP, with IC50 of 1.18 μM for FABP 1. FABP4-IN-4 improves the glucose tolerance, reduces the level of blood glucose, plasma lipids and hepatic inflammatory factors, attenuates hepatic steatosis, and exhibits anti-inflammatory effects in mouse diet-induced obesity models[1].

IC50 & Target

IC50: 1.18 μM (FABP 1)
Molecular Weight

509.60

Formula

C25H23N3O5S2
SMILES

O=S(C1=C(N=CC=C2)C2=CC=C1)(N3CCN(S(C4=C(C5=CC=CC(O)=C5)C=CC=C4)(=O)=O)CC3)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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FABP4-IN-4 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

FABP4-IN-4FABPFatty acid-binding proteinC57BL/6J mouseobesityorally activehepatic steatosisInhibitorinhibitorinhibit

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