2. Protein Tyrosine Kinase/RTK
  3. FAK
  4. FAK-IN-19

FAK-IN-19 (ligand3) is an inhibitor in a co-crystal structure with FAK. FAK-IN-19 has anticancer effects.

For research use only. We do not sell to patients.

FAK-IN-19 Chemical Structure

FAK-IN-19 Chemical Structure

CAS No. : 863599-15-9

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 In-stock
Solution
10 mM * 1 mL in DMSO In-stock
Solid
5 mg In-stock
10 mg In-stock
25 mg In-stock
50 mg In-stock
100 mg   Get quote  
200 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

FAK-IN-19 Related Antibodies

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Description

FAK-IN-19 (ligand3) is an inhibitor in a co-crystal structure with FAK. FAK-IN-19 has anticancer effects[1].

Molecular Weight

377.40

Formula

C20H19N5O3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

COC(C=C1NC2=NC3=C(C=N2)C=CN3C4=NC=CC=C4)=C(C(OC)=C1)OC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (264.97 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6497 mL 13.2485 mL 26.4971 mL
5 mM 0.5299 mL 2.6497 mL 5.2994 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.6497 mL 13.2485 mL 26.4971 mL 66.2427 mL
5 mM 0.5299 mL 2.6497 mL 5.2994 mL 13.2485 mL
10 mM 0.2650 mL 1.3249 mL 2.6497 mL 6.6243 mL
15 mM 0.1766 mL 0.8832 mL 1.7665 mL 4.4162 mL
20 mM 0.1325 mL 0.6624 mL 1.3249 mL 3.3121 mL
25 mM 0.1060 mL 0.5299 mL 1.0599 mL 2.6497 mL
30 mM 0.0883 mL 0.4416 mL 0.8832 mL 2.2081 mL
40 mM 0.0662 mL 0.3312 mL 0.6624 mL 1.6561 mL
50 mM 0.0530 mL 0.2650 mL 0.5299 mL 1.3249 mL
60 mM 0.0442 mL 0.2208 mL 0.4416 mL 1.1040 mL
80 mM 0.0331 mL 0.1656 mL 0.3312 mL 0.8280 mL
100 mM 0.0265 mL 0.1325 mL 0.2650 mL 0.6624 mL
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FAK-IN-19 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

FAK-IN-19863599-15-9FAKPTK2 protein tyrosine kinase 2PTK2Focal adhesion kinaseFAK inhibitorInhibitorinhibitorinhibit

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