1. Protein Tyrosine Kinase/RTK Apoptosis
  2. VEGFR PDGFR Apoptosis
  3. Famitinib (Standard)

Famitinib (Standard) is the analytical standard of Famitinib. This product is intended for research and analytical applications. Famitinib (SHR1020), an orally active multi-targeted kinase inhibitor, inhibits the activity of c-kit, VEGFR-2 and PDGFRβ with IC50 values of 2.3 nM, 4.7 nM and 6.6 nM, respectively. Famitinib exerts powerful antitumor activity in human gastric cancer cells and xenografts. Famitinib triggers apoptosis.

For research use only. We do not sell to patients.

Famitinib (Standard) Chemical Structure

Famitinib (Standard) Chemical Structure

CAS No. : 1044040-56-3

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Description
Molecular Weight

410.48

Formula

C23H27FN4O2

CAS No.
SMILES

O=C1C2=C(NC(/C=C3C(NC4=C\3C=C(F)C=C4)=O)=C2C)CCN1CCN(CC)CC

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Famitinib (Standard)
Cat. No.:
HY-108713R
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