FAUC-312

Cat. No.: HY-121740: FAQs
Data Sheet Handling Instructions

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FAUC-312, a tetrahydropyrimidine, is a strong and highly selective dopamine D4 receptor partial agonist (K_i=1.5 nM).

For research use only. We do not sell to patients.

FAUC-312 Chemical Structure

CAS No. : 562104-72-7

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Purity & Documentation
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Description

FAUC-312, a tetrahydropyrimidine, is a strong and highly selective dopamine D4 receptor partial agonist (K_i=1.5 nM)^[1].

IC₅₀ & Target^[1]

Dopamine D4 receptor

1.5 nM (Ki)

Dopamine D1 receptor

29000 nM (Ki)

Dopamine D2 receptor

25000 nM (Ki)

Dopamine D3 receptor

13000 nM (Ki)

Molecular Weight

334.46

Formula

C₂₁H₂₆N₄

CAS No.

562104-72-7

SMILES

C1(C2=CC=CC=C2)=NCC[C@H](N1)CN3CCN(CC3)C4=CC=CC=C4

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Jürgen Einsiedel, et al. Cyclic amidines as benzamide bioisosteres: EPC synthesis and SAR studies leading to the selective dopamine D4 receptor agonist FAUC 312. Bioorg Med Chem Lett. 2003 Mar 10;13(5):851-4. [Content Brief]

FAUC-312 Related Classifications

Neurological Disease

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

FAUC-312562104-72-7FAUC312FAUC 312Dopamine ReceptorInhibitorinhibitorinhibit

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