1. Neuronal Signaling
  2. Cholinesterase (ChE)
  3. Feralolide

Feralolide is a dihydroisocoumarin isolated from the methanolic extract of aloe vera resin. Feralolide is also a dual inhibitor of AChE and BuChE, with IC50s of 55 μg/mL and 52 μg/mL respectively. Feralolide has antioxidant activity and inhibits 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2, 2′-azinobis-3-ethylbenzothiazoline-6-sulfonic acid (ABTS). Feralolide could be used in research into cognitive disorders such as Alzheimer's disease, potentially restoring and enhancing memory.

For research use only. We do not sell to patients.

Feralolide Chemical Structure

Feralolide Chemical Structure

CAS No. : 149418-38-2

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Description

Feralolide is a dihydroisocoumarin isolated from the methanolic extract of aloe vera resin. Feralolide is also a dual inhibitor of AChE and BuChE, with IC50s of 55 μg/mL and 52 μg/mL respectively. Feralolide has antioxidant activity and inhibits 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2, 2′-azinobis-3-ethylbenzothiazoline-6-sulfonic acid (ABTS). Feralolide could be used in research into cognitive disorders such as Alzheimer's disease, potentially restoring and enhancing memory[1].

IC50 & Target

IC50: 55 μg/mL (AChE), 52 μg/mL (BuChE)[1]

Molecular Weight

344.32

Formula

C18H16O7

CAS No.
SMILES

O=C1C2=C(O)C=C(O)C=C2C[C@H](O1)CC3=C(C(O)=CC(O)=C3)C(C)=O

Structure Classification
Initial Source
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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Feralolide
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HY-N11997
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