2. GPCR/G Protein Neuronal Signaling
  3. Adenylate Cyclase Dopamine Transporter
  4. Fipexide hydrochloride

Fipexide hydrochloride, a parachloro-phenossiacetic acid derivative, is an orally active nootropic agent. Fipexide hydrochloride reduces striatal adenylate cyclase activity. Fipexide hydrochloride has positive effect on cognitive performance by dopaminergic neurotransmission. Fipexide hydrochloride is used for senile dementia research. Fipexide hydrochloride acts as a chemical inducer in callus formation, shoot regeneration and Agrobacterium infection.

For research use only. We do not sell to patients.

Fipexide hydrochloride Chemical Structure

Fipexide hydrochloride Chemical Structure

CAS No. : 34161-23-4

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Based on 1 publication(s) in Google Scholar

Other Forms of Fipexide hydrochloride:

Fipexide hydrochloride Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Fipexide hydrochloride

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Fipexide hydrochloride, a parachloro-phenossiacetic acid derivative, is an orally active nootropic agent. Fipexide hydrochloride reduces striatal adenylate cyclase activity. Fipexide hydrochloride has positive effect on cognitive performance by dopaminergic neurotransmission. Fipexide hydrochloride is used for senile dementia research. Fipexide hydrochloride acts as a chemical inducer in callus formation, shoot regeneration and Agrobacterium infection[1][2].

In Vitro

Fipexide (50 μM; for 15 days) hydrochloride shows simple structures, which contained epidermal regions with well-expanded cells and actively dividing regions for Arabidopsis wild-type seedlings[2]

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Fipexide hydrochloride Related Antibodies
In Vivo

Fipexide (10 mg/kg; orally; 5-10 days) hydrochloride completely abolishes the memory deficit produced by kindling in rats[3]

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Kindled rats[3]
Dosage: 10 mg/kg
Administration: Orally; 5-10 days
Result: Completely abolishes the memory deficit produced by kindling.
Antagonized the amnestic effect of Pentylenetetrazole (PTZ) -kindling.
Molecular Weight

425.31

Formula

C20H22Cl2N2O4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

ClC1=CC=C(OCC(N2CCN(CC3=CC=C(OCO4)C4=C3)CC2)=O)C=C1.[H]Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (117.56 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3512 mL 11.7561 mL 23.5123 mL
5 mM 0.4702 mL 2.3512 mL 4.7025 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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C2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

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g

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.88%

COA (245 KB) LCMS (86 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.3512 mL 11.7561 mL 23.5123 mL 58.7807 mL
5 mM 0.4702 mL 2.3512 mL 4.7025 mL 11.7561 mL
10 mM 0.2351 mL 1.1756 mL 2.3512 mL 5.8781 mL
15 mM 0.1567 mL 0.7837 mL 1.5675 mL 3.9187 mL
20 mM 0.1176 mL 0.5878 mL 1.1756 mL 2.9390 mL
25 mM 0.0940 mL 0.4702 mL 0.9405 mL 2.3512 mL
30 mM 0.0784 mL 0.3919 mL 0.7837 mL 1.9594 mL
40 mM 0.0588 mL 0.2939 mL 0.5878 mL 1.4695 mL
50 mM 0.0470 mL 0.2351 mL 0.4702 mL 1.1756 mL
60 mM 0.0392 mL 0.1959 mL 0.3919 mL 0.9797 mL
80 mM 0.0294 mL 0.1470 mL 0.2939 mL 0.7348 mL
100 mM 0.0235 mL 0.1176 mL 0.2351 mL 0.5878 mL
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Fipexide hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Fipexide34161-23-4Adenylate CyclaseDopamine TransporterAdenylyl cyclaseDATSLC6A3parachloro-phenossiaceticacidnootropiccognitiveperformancedopaminergicneurotransmissionseniledementiaInhibitorinhibitorinhibit

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