2. Metabolic Enzyme/Protease Vitamin D Related/Nuclear Receptor
  3. LXR
  4. FITC-GW3965

FITC-GW3965 is a fluorescence-labelled liver X receptor β (LXRβ) agonist GW3965 (HY-10627). FITC-GW3965 is a tracer, that can be designed by replacing the trifluoromethyl of GW3965 with an amide to link the FITC. FITC-GW3965 can be used to study the function of LXRβ.

For research use only. We do not sell to patients.

FITC-GW3965 Chemical Structure

FITC-GW3965 Chemical Structure

CAS No. : 2374144-23-5

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5 mg USD 743 In-stock
10 mg USD 1190 In-stock
25 mg USD 2500 In-stock
50 mg USD 4000 In-stock
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Based on 1 publication(s) in Google Scholar

FITC-GW3965 Related Antibodies

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Description

FITC-GW3965 is a fluorescence-labelled liver X receptor β (LXRβ) agonist GW3965 (HY-10627). FITC-GW3965 is a tracer, that can be designed by replacing the trifluoromethyl of GW3965 with an amide to link the FITC. FITC-GW3965 can be used to study the function of LXRβ[1].

IC50 & Target

LXRβ[1]
Molecular Weight

997.16

Formula

C59H56N4O9S
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C(CC1=CC(OCCCN(CC(C2=CC=CC=C2)C3=CC=CC=C3)CC4=CC(NC(CCCCCNC(NC5=CC=C6C(C(OC67C8=CC=C(C=C8OC9=CC(O)=CC=C97)O)=O)=C5)=S)=O)=CC=C4)=CC=C1)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 50 mg/mL (50.14 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.0028 mL 5.0142 mL 10.0285 mL
5 mM 0.2006 mL 1.0028 mL 2.0057 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

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Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.0028 mL 5.0142 mL 10.0285 mL 25.0712 mL
5 mM 0.2006 mL 1.0028 mL 2.0057 mL 5.0142 mL
10 mM 0.1003 mL 0.5014 mL 1.0028 mL 2.5071 mL
15 mM 0.0669 mL 0.3343 mL 0.6686 mL 1.6714 mL
20 mM 0.0501 mL 0.2507 mL 0.5014 mL 1.2536 mL
25 mM 0.0401 mL 0.2006 mL 0.4011 mL 1.0028 mL
30 mM 0.0334 mL 0.1671 mL 0.3343 mL 0.8357 mL
40 mM 0.0251 mL 0.1254 mL 0.2507 mL 0.6268 mL
50 mM 0.0201 mL 0.1003 mL 0.2006 mL 0.5014 mL
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FITC-GW3965 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

FITC-GW39652374144-23-5LXRLiver X receptorInhibitorinhibitorinhibit

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