2. Others Neuronal Signaling
  3. Serotonin Transporter Isotope-Labeled Compounds
  4. Fluoxetine-d5 hydrochloride

Fluoxetine-d5 hydrochloride  (Synonyms: LY 110140-d5)

Cat. No.: HY-B0102AS Purity: 99.65%
SDS COA Handling Instructions Technical Support

Fluoxetine-d5 (hydrochloride) is the deuterium labeled Fluoxetine hydrochloride (LY 110140)[1].

For research use only. We do not sell to patients.

Fluoxetine-d<sub>5</sub> hydrochloride Chemical Structure

Fluoxetine-d5 hydrochloride Chemical Structure

CAS No. : 1173020-43-3

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Based on 1 publication(s) in Google Scholar

Fluoxetine-d5 hydrochloride Related Antibodies

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Description

Fluoxetine-d5 (hydrochloride) is the deuterium labeled Fluoxetine hydrochloride (LY 110140)[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Fluoxetine-d5 hydrochloride Related Antibodies
Molecular Weight

350.82

Formula

C17H14D5ClF3NO
CAS No.
Unlabeled CAS
Appearance

Solid

Color

White to off-white

SMILES

FC(F)(F)C(C=C1)=CC=C1OC(C2=C([2H])C([2H])=C([2H])C([2H])=C2[2H])CCNC.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 12.5 mg/mL (35.63 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.8505 mL 14.2523 mL 28.5046 mL
5 mM 0.5701 mL 2.8505 mL 5.7009 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.65%

SDS (398 KB)

COA (252 KB) HNMR (1365 KB) RP-HPLC (878 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.8505 mL 14.2523 mL 28.5046 mL 71.2616 mL
5 mM 0.5701 mL 2.8505 mL 5.7009 mL 14.2523 mL
10 mM 0.2850 mL 1.4252 mL 2.8505 mL 7.1262 mL
15 mM 0.1900 mL 0.9502 mL 1.9003 mL 4.7508 mL
20 mM 0.1425 mL 0.7126 mL 1.4252 mL 3.5631 mL
25 mM 0.1140 mL 0.5701 mL 1.1402 mL 2.8505 mL
30 mM 0.0950 mL 0.4751 mL 0.9502 mL 2.3754 mL
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Fluoxetine-d5 hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Fluoxetine-d51173020-43-3LY 110140-d5Serotonin TransporterIsotope-Labeled Compounds5-HTTSERTSLC6A4Inhibitorinhibitorinhibit

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