2. Membrane Transporter/Ion Channel
  3. Calmodulin
  4. Fluphenazine-N-2-chloroethane hydrochloride

Fluphenazine-N-2-chloroethane hydrochloride  (Synonyms: SKF-7171A hydrochloride)

Cat. No.: HY-133782 Purity: 95.5%
SDS COA Handling Instructions Technical Support

Fluphenazine-N-2-chloroethane (SKF-7171A) hydrochloride is a potent irreversible calmodulin antagonist.

For research use only. We do not sell to patients.

Fluphenazine-N-2-chloroethane hydrochloride Chemical Structure

Fluphenazine-N-2-chloroethane hydrochloride Chemical Structure

CAS No. : 3892-78-2

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Based on 1 publication(s) in Google Scholar

Fluphenazine-N-2-chloroethane hydrochloride Related Antibodies

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Description

Fluphenazine-N-2-chloroethane (SKF-7171A) hydrochloride is a potent irreversible calmodulin antagonist[1][2].

In Vitro

Fluphenazine-N-2-chloroethane hydrochloride (10 µM) decrease the NO production induced by CORM-2 (HY-W033577) at 0.1 mM in acinar cells[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Fluphenazine-N-2-chloroethane hydrochloride Related Antibodies
Molecular Weight

528.89

Formula

C22H27Cl3F3N3S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

FC(C(C=C1N2CCCN3CCN(CCCl)CC3)=CC=C1SC4=C2C=CC=C4)(F)F.Cl.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 10 mg/mL (18.91 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8908 mL 9.4538 mL 18.9075 mL
5 mM 0.3782 mL 1.8908 mL 3.7815 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 95.5%

SDS (252 KB)

COA (249 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.8908 mL 9.4538 mL 18.9075 mL 47.2688 mL
5 mM 0.3782 mL 1.8908 mL 3.7815 mL 9.4538 mL
10 mM 0.1891 mL 0.9454 mL 1.8908 mL 4.7269 mL
15 mM 0.1261 mL 0.6303 mL 1.2605 mL 3.1513 mL
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Fluphenazine-N-2-chloroethane hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Fluphenazine-N-2-chloroethane3892-78-2SKF-7171ACalmodulinCaMCalcium-Modulated ProteinCORM-2acinar cellsNOInhibitorinhibitorinhibit

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