Fmoc-Gly-NH-CH2-O-CH2COOH

Cat. No.: HY-43279 Purity: 99.13%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Fmoc-Gly-NH-CH2-O-CH2COOH is an ADC linker. Fmoc-Gly-NH-CH2-O-CH2COOH can be used for synthesis of ADCs.

For research use only. We do not sell to patients.

Fmoc-Gly-NH-CH2-O-CH2COOH Chemical Structure

CAS No. : 1599440-08-0

Size	Price	Stock	Quantity
Free Sample (0.1 - 0.5 mg)		Apply Now
100 mg	USD 70	In-stock	Estimated Time of Arrival: December 31
250 mg	USD 140	In-stock	Estimated Time of Arrival: December 31
1 g	USD 358	In-stock	Estimated Time of Arrival: December 31
5 g		Get quote
10 g		Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Fmoc-Gly-NH-CH2-O-CH2COOH is an ADC linker. Fmoc-Gly-NH-CH2-O-CH2COOH can be used for synthesis of ADCs^[1].

Molecular Weight

384.38

Formula

C₂₀H₂₀N₂O₆

CAS No.

1599440-08-0

Appearance

Solid

Color

White to off-white

SMILES

O=C(O)COCNC(CNC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 175 mg/mL (455.28 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.6016 mL	13.0080 mL	26.0159 mL
5 mM	0.5203 mL	2.6016 mL	5.2032 mL
10 mM	0.2602 mL	1.3008 mL	2.6016 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.13%

Select Batch:

Data Sheet (267 KB) SDS (393 KB)

COA (247 KB) HNMR (270 KB) RP-HPLC (262 KB) LCMS (98 KB)

Handling Instructions (2659 KB)

References

[1]. Tsuda Toshifumi, et al. Novel cyclic dinucleotide derivative and its antibody-drug conjugate having STING agonist activity. Patent. WO2020050406.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.6016 mL	13.0080 mL	26.0159 mL	65.0398 mL
	5 mM	0.5203 mL	2.6016 mL	5.2032 mL	13.0080 mL
	10 mM	0.2602 mL	1.3008 mL	2.6016 mL	6.5040 mL
	15 mM	0.1734 mL	0.8672 mL	1.7344 mL	4.3360 mL
	20 mM	0.1301 mL	0.6504 mL	1.3008 mL	3.2520 mL
	25 mM	0.1041 mL	0.5203 mL	1.0406 mL	2.6016 mL
	30 mM	0.0867 mL	0.4336 mL	0.8672 mL	2.1680 mL
	40 mM	0.0650 mL	0.3252 mL	0.6504 mL	1.6260 mL
	50 mM	0.0520 mL	0.2602 mL	0.5203 mL	1.3008 mL
	60 mM	0.0434 mL	0.2168 mL	0.4336 mL	1.0840 mL
	80 mM	0.0325 mL	0.1626 mL	0.3252 mL	0.8130 mL
	100 mM	0.0260 mL	0.1301 mL	0.2602 mL	0.6504 mL