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  3. Fosbretabulin tromethamine

Fosbretabulin (tromethamine), also known as combretastatin A4 phosphate (CA4P), is a vascular disrupting agent evaluated for its efficacy against anaplastic thyroid carcinoma (ATC). It targets tumor neovasculature, causing acute and reversible reductions in tumor blood flow and central necrosis.

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Fosbretabulin tromethamine Chemical Structure

Fosbretabulin tromethamine Chemical Structure

CAS No. : 404886-32-4

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Description

Fosbretabulin (tromethamine), also known as combretastatin A4 phosphate (CA4P), is a vascular disrupting agent evaluated for its efficacy against anaplastic thyroid carcinoma (ATC). It targets tumor neovasculature, causing acute and reversible reductions in tumor blood flow and central necrosis[1].

Molecular Weight

517.46

Formula

C22H32NO11P

CAS No.
SMILES

OCC(CO)(N)CO.O=P(O)(O)OC1=C(C=CC(/C=C\C2=CC(OC)=C(C(OC)=C2)OC)=C1)OC

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Fosbretabulin tromethamine Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Fosbretabulin tromethamine
Cat. No.:
HY-15855
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