1. Stem Cell/Wnt TGF-beta/Smad
  2. TGF-beta/Smad
  3. Fresolimumab

Fresolimumab  (Synonyms: GC1008)

Cat. No.: HY-P99020 Purity: 99.51%
Data Sheet Technical Support

Fresolimumab (GC1008) is a human monoclonal antibody against TGF-β that neutralizes all mammalian active subtypes of TGF-β. The binding affinity of Fresolimumab to TGF-β2 is 1.8 nM. Fresolimumab radiolabeled with 89Zr can be used for PET analysis of TGF-β expression, antibody uptake and organ distribution. Fresolimumab can be used in the study of cancer, osteogenesis imperfecta, fibrosis and kidney disease.

For research use only. We do not sell to patients.

CAS No. : 948564-73-6

Size Price Stock Quantity
1 mg USD 720 In-stock
5 mg USD 2050 In-stock
10 mg USD 3250 In-stock
50 mg   Get quote  
100 mg   Get quote  

Get it by April 8 for select sizes. Order within 22 hrs 39 mins.

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Fresolimumab

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Fresolimumab (GC1008) is a human monoclonal antibody against TGF-β that neutralizes all mammalian active subtypes of TGF-β. The binding affinity of Fresolimumab to TGF-β2 is 1.8 nM. Fresolimumab radiolabeled with 89Zr can be used for PET analysis of TGF-β expression, antibody uptake and organ distribution. Fresolimumab can be used in the study of cancer, osteogenesis imperfecta, fibrosis and kidney disease[1][2][3].

Isotype

Human IgG4 kappa

Recommend Isotype Controls
Species

Human

Clinical Trial
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Fresolimumab]

Shipping

Shipping with dry ice.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Format
  • Human IgG4 kappa
Biological Activity
  • Immobilized TGF beta 1/TGFB1 Protein, Human can bind Fresolimumab. The EC50 for this effect is 67.28 ng/mL.
Purity & Documentation

Purity: 99.51%

References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Requested Quantity *

Applicant Name *

 

Salutation

Email Address *

 

Phone Number *

Department

 

Organization Name *

City

State

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Fresolimumab
Cat. No.:
HY-P99020
Quantity:
MCE Japan Authorized Agent: