2. Metabolic Enzyme/Protease
  3. Cathepsin
  4. Gü1303

Gü1303 is a potent, reversible, slow-binding cathepsin K (CatK) inhibitor with a Ki of 0.91 nM for mature CatK (mCatK). Gü1303 suppresses the autocatalytic activation of the cathepsin K zymogen.

For research use only. We do not sell to patients.

Gü1303 Chemical Structure

Gü1303 Chemical Structure

CAS No. : 1043922-53-7

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Gü1303 Related Antibodies

Top Publications Citing Use of Products

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Cathepsin B Cathepsin C Cathepsin D Cathepsin E Cathepsin K Cathepsin L Cathepsin S

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Description

Gü1303 is a potent, reversible, slow-binding cathepsin K (CatK) inhibitor with a Ki of 0.91 nM for mature CatK (mCatK). Gü1303 suppresses the autocatalytic activation of the cathepsin K zymogen[1].

IC50 & Target

Ki: 0.91 nM (mCatK)[1]
Molecular Weight

366.41

Formula

C20H22N4O3
CAS No.
SMILES

CN(N(C([C@@H](NC(OCC1=CC=CC=C1)=O)CC2=CC=CC=C2)=O)C)C#N
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Gü1303 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Gü13031043922-53-7Cathepsincathepsin Kprotease inhibitorosteoporosisarthritisbone metastasisInhibitorinhibitorinhibit

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