1. Epigenetics
  2. Histone Methyltransferase
  3. G9D-4

G9D-4 is a potent degrader of G9a, with the DC50 value of 0.1 μM in PANC-1 cells and do not directly perturb GLP protein, with the DC50 of >10 μM. G9D-4 plays an important role in pancreatic cancer research.

For research use only. We do not sell to patients.

G9D-4 Chemical Structure

G9D-4 Chemical Structure

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Description

G9D-4 is a potent degrader of G9a, with the DC50 value of 0.1 μM in PANC-1 cells and do not directly perturb GLP protein, with the DC50 of >10 μM. G9D-4 plays an important role in pancreatic cancer research[1].

Molecular Weight

950.22

Formula

C53H75N9O7

SMILES

COC1=CC2=C(C=C1OCCCN3CCCC3)N=C(C4CCCCC4)N=C2NC5CCN(CC5)CCCC(NCCCCCCCCCNC6=C(C7=CC=C6)C(N(C7=O)C8C(NC(CC8)=O)=O)=O)=O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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G9D-4
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HY-162749
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