2. Peptides
  3. Peptide and Derivatives
  4. Peptide Epitopes
  5. GADGVGKSAL

GADGVGKSAL is a mutant KRAS G12D 10mer peptide. GADGVGKSAL can be used as an immunogenic neoantigen for cancer immunotherapy research.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

GADGVGKSAL Chemical Structure

GADGVGKSAL Chemical Structure

CAS No. : 199477-24-2

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Based on 1 publication(s) in Google Scholar

GADGVGKSAL Related Antibodies

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Description

GADGVGKSAL is a mutant KRAS G12D 10mer peptide. GADGVGKSAL can be used as an immunogenic neoantigen for cancer immunotherapy research[1].

In Vitro

GAGGVGKSAL can refold with HLA-C*05:01, which is a potential allele to present KRAS G12D 10mer peptide.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

GADGVGKSAL Related Antibodies
Molecular Weight

873.95

Formula

C36H63N11O14
CAS No.
Appearance

Solid

Color

Colorless to off-white

Sequence

Gly-Ala-Asp-Gly-Val-Gly-Lys-Ser-Ala-Leu
Sequence Shortening

GADGVGKSAL
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (114.42 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.1442 mL 5.7212 mL 11.4423 mL
5 mM 0.2288 mL 1.1442 mL 2.2885 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.1442 mL 5.7212 mL 11.4423 mL 28.6058 mL
5 mM 0.2288 mL 1.1442 mL 2.2885 mL 5.7212 mL
10 mM 0.1144 mL 0.5721 mL 1.1442 mL 2.8606 mL
15 mM 0.0763 mL 0.3814 mL 0.7628 mL 1.9071 mL
20 mM 0.0572 mL 0.2861 mL 0.5721 mL 1.4303 mL
25 mM 0.0458 mL 0.2288 mL 0.4577 mL 1.1442 mL
30 mM 0.0381 mL 0.1907 mL 0.3814 mL 0.9535 mL
40 mM 0.0286 mL 0.1430 mL 0.2861 mL 0.7151 mL
50 mM 0.0229 mL 0.1144 mL 0.2288 mL 0.5721 mL
60 mM 0.0191 mL 0.0954 mL 0.1907 mL 0.4768 mL
80 mM 0.0143 mL 0.0715 mL 0.1430 mL 0.3576 mL
100 mM 0.0114 mL 0.0572 mL 0.1144 mL 0.2861 mL
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GADGVGKSAL Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GADGVGKSAL199477-24-2OthersKRAS G12Dcancer immunotherapytumorneoantigensInhibitorinhibitorinhibit

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