2. Metabolic Enzyme/Protease Vitamin D Related/Nuclear Receptor Cell Cycle/DNA Damage Others
  3. Cytochrome P450 PPAR Isotope-Labeled Compounds
  4. Gemfibrozil-d6-1

Gemfibrozil-d6-1 (CI-719-d6-1) is the deuterium labeled Gemfibrozil (HY-B0258). Gemfibrozil is an activator of PPAR-α, used as a lipid-lowering agent; Gemfibrozil is also a nonselective inhibitor of several P450 isoforms, with Ki values for CYP2C9, 2C19, 2C8, and 1A2 of 5.8, 24, 69, and 82 μM, respectively.

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Gemfibrozil-d<sub>6</sub>-1 Chemical Structure

Gemfibrozil-d6-1 Chemical Structure

CAS No. : 1160569-36-7

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Other Forms of Gemfibrozil-d6-1:

Gemfibrozil-d6-1 Related Antibodies

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CYP1 CYP2 CYP3 CYP4 CYP11 CYP17 Aromatase/CYP19A1 CYP26 CYP51 CYP2D6 CYP2C9 CYP2C19 CYP3A4 CYP17A1

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PPARα PPARβ/δ PPARγ PPAR PPARδ

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Description

Gemfibrozil-d6-1 (CI-719-d6-1) is the deuterium labeled Gemfibrozil (HY-B0258). Gemfibrozil is an activator of PPAR-α, used as a lipid-lowering agent; Gemfibrozil is also a nonselective inhibitor of several P450 isoforms, with Ki values for CYP2C9, 2C19, 2C8, and 1A2 of 5.8, 24, 69, and 82 μM, respectively[1].

Molecular Weight

256.37

Formula

C15H16D6O3
CAS No.
Unlabeled CAS

25812-30-0
SMILES

O=C(C(C)(CCCOC1=CC(C([2H])([2H])[2H])=CC=C1C([2H])([2H])[2H])C)O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Gemfibrozil-d6-1 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Gemfibrozil-d6-11160569-36-7CI-719-d6-1Cytochrome P450PPARIsotope-Labeled CompoundsCYPsPeroxisome proliferator-activated receptorsInhibitorinhibitorinhibit

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