DEFB4B - defensin beta 4B Gene

Homo sapiens

Also known as DEFB4P

Gene ID: 100289462 | Gene type: protein coding

About DEFB4B

This gene has 1 transcript (splice variant), 1 gene allele, 8 orthologues and 3 paralogues. Biased expression in gall bladder (RPKM 1.0), esophagus (RPKM 0.7) and 3 other tissues.

Summary

Defensins form a family of microbicidal and cytotoxic Peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 4, an Antibiotic peptide which is locally regulated by inflammation. [provided by RefSeq, Oct 2014]

DEFB4B Products(1)

mRNA	Protein	Name
NM_001205266.2	NP_001192195.1	beta-defensin 4B precursor

DEFB4B Protein Structure

Defensin_beta

0
64 a.a.

Protein Preferred Names

Protein Names

beta-defensin 4B

beta defensin 2

DEFB4B Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	DEFB4A	O15263	ZMPSTE24	Homo sapiens	O75844	Anti Tag CoIP	33961781
Intra	DEFB4A	O15263	ZMPSTE24	Homo sapiens	O75844	Anti Tag CoIP	28514442

Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant DEFB4B Proteins

Cat. No.	Product Name	Accession	Purity
HY-P7135	BD-2 Protein, Human	O15263 (G24-P64)	≥95%

Related Diseases

Diseases

Alias

Erythrasma

Infection Due To Corynebacterium Minutissimum

Tinea Pedis

Athlete'S Foot	Dermatophytosis Of Foot
Ringworm Of Foot	Moccasin Foot

Acute Pericementitis

Acute Periodontitis	Aggressive And Acute Periodontitis
Peridental Infection	Periodontal Infection

Leukorrhea

Discharge - Leukorrhea

Leukorrhea Of Vagina

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03681	DEFB4B Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

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