CCT7 - chaperonin containing TCP1 subunit 7 Gene

Homo sapiens

Also known as CCTH; CCTETA; NIP7-1; TCP1ETA

Gene ID: 10574 | Gene type: protein coding

About CCT7

Cytogenetic location: 2p13.2 Genomic coordinates (GRCh38): 2:73,234,308-73,253,005 (from NCBI)

This gene has 16 transcripts (splice variants), 231 orthologues and 13 paralogues. Ubiquitous expression in testis (RPKM 102.9), adrenal (RPKM 73.8) and 25 other tissues.

Summary

This gene encodes a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 6. [provided by RefSeq, Oct 2009]

CCT7 Products(4)

mRNA	Protein	Name
NM_001009570.3	NP_001009570.1	T-complex protein 1 subunit eta isoform b
NM_001166284.2	NP_001159756.1	T-complex protein 1 subunit eta isoform c
NM_001166285.2	NP_001159757.1	T-complex protein 1 subunit eta isoform d
NM_006429.4	NP_006420.1	T-complex protein 1 subunit eta isoform a

CCT7 Protein Structure

Cpn60_TCP1

0
100
200
300
400
500
543 a.a.

Protein Preferred Names

Protein Names

T-complex protein 1 subunit eta

CCT-eta

Related Diseases

Diseases

Alias

Myocardial Infarction

Heart Attack	Myocardial Infarction, Susceptibility To
Myocardial Infarction 1	Myocardial Infarction, Protection Against
Myocardial Infarction, Decreased Susceptibility To	Myocardial Infarction, Decreased
Myocardial Infarct	MCI1
Premature Myocardial Infarction	Myocardial Infarction, Susceptibility To, Type 1

Babesiosis

Babesiasis	Infection By Babesia
Piroplasmosis	Human Babesiosis
Babesia Parasite Infection	Piroplasma Infection

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02184	CCT7 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	CCT7	VGNC	VGNC:27000
Mus musculus	CCT7	MGD	MGI:107184
Rattus norvegicus	CCT7	RGD	RGD:1306422
Macaca mulatta	CCT7	VGNC	VGNC:103798
Felis catus	CCT7	VGNC	VGNC:60581

Name
Email *

	Sorry, but the email address you supplied was invalid.