1. Gene
  2. FGL2 - fibrinogen like 2 Gene

FGL2 - fibrinogen like 2 Gene

Homo sapiens

Also known as T49; pT49

Gene ID: 10875 | Gene type: protein coding

About FGL2

Cytogenetic location: 7q11.23 Genomic coordinates (GRCh38): 7:77,193,369-77,199,819 (from NCBI)

This gene has 2 transcripts (splice variants), 278 orthologues and 25 paralogues. Broad expression in spleen (RPKM 83.3), appendix (RPKM 61.0) and 22 other tissues.

Summary

The protein encoded by this gene is a secreted protein that is similar to the beta- and gamma-chains of fibrinogen. The carboxyl-terminus of the encoded protein consists of the fibrinogen-related domains (FRED). The encoded protein forms a tetrameric complex which is stabilized by interchain disulfide bonds. This protein may play a role in physiologic functions at mucosal sites. [provided by RefSeq, Jul 2008]

FGL2 Products(1)

mRNA Protein Name
NM_006682.3 NP_006673.1 fibroleukin precursor

FGL2 Protein Structure

Fibrinogen_C

Fibrinogen_C: Fibrinogen beta and gamma chains, C-terminal globular domain (210 - 435)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 439 a.a.
Protein Preferred Names Protein Names

fibroleukin

fibrinogen-like protein 2

Recombinant FGL2 Proteins

Cat. No. Product Name Accession Purity
HY-P700721 FGL2 Protein, Human (HEK293, His-Avi, Flag) Q14314 (V205-P439) ≥95%
HY-P700987 FGL2 Protein, Human (Biotinylated, HEK293, His-Avi, Flag) Q14314 (V205-P439) ≥95%
HY-P701078 FGL2 Protein, Human (HEK293, hFc-Flag) Q14314 (V205-P439) ≥95%

Related Diseases

Diseases Alias
Viral Hepatitis

Animal Viral Hepatitis

Hepatitis, Viral, Animal

Human Viral Hepatitis

Viral Hepatitis With Hepatic Coma

Hepatitis B

Chronic Hepatitis B

Hepatitis B Infection

Serum Hepatitis

HBV

Hepatitis B Chronic

Hbv, Susceptibility To

Hepatitis B, Chronic

Chronic Hepatitis B Without Delta Agent

Chronic Hbv - [Hepatitis B Virus] Infection

Hepatitis B Nos

Chronic Type B Viral Hepatitis

Hep B Nos

Ileum Cancer

Ileal Neoplasm

Malignant Neoplasm Of Ileum

Ileal Cancer

Ileal Neoplasms

Autoimmune Glomerulonephritis
Pontocerebellar Hypoplasia, Type 3

Pontocerebellar Hypoplasia Type 3

Cerebellar Atrophy With Progressive Microcephaly

PCH3

Clam

Pch With Optic Atrophy

Pontocerebellar Hypoplasia 3

Hypoplasia, Pontocerebellar, Type 3

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Felis catus FGL2 VGNC VGNC:80044
Rattus norvegicus FGL2 RGD RGD:620170
Mus musculus FGL2 MGD MGI:103266
Macaca mulatta FGL2 VGNC VGNC:72657
Bos taurus FGL2 VGNC VGNC:28993
Canis familiaris FGL2 VGNC VGNC:40865
Macaca fascicularis FGL2 NCBI NCBI:102123631
Others FGL2 NCBI