FGL2 - fibrinogen like 2 Gene

Homo sapiens

Also known as T49; pT49

Gene ID: 10875 | Gene type: protein coding

About FGL2

Cytogenetic location: 7q11.23 Genomic coordinates (GRCh38): 7:77,193,369-77,199,819 (from NCBI)

This gene has 2 transcripts (splice variants), 278 orthologues and 25 paralogues. Broad expression in spleen (RPKM 83.3), appendix (RPKM 61.0) and 22 other tissues.

Summary

The protein encoded by this gene is a secreted protein that is similar to the beta- and gamma-chains of fibrinogen. The carboxyl-terminus of the encoded protein consists of the fibrinogen-related domains (FRED). The encoded protein forms a tetrameric complex which is stabilized by interchain disulfide bonds. This protein may play a role in physiologic functions at mucosal sites. [provided by RefSeq, Jul 2008]

FGL2 Products(1)

mRNA	Protein	Name
NM_006682.3	NP_006673.1	fibroleukin precursor

FGL2 Protein Structure

Fibrinogen_C

0
100
200
300
400
439 a.a.

Protein Preferred Names

Protein Names

fibroleukin

fibrinogen-like protein 2

Recombinant FGL2 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P700721	FGL2 Protein, Human (HEK293, His-Avi, Flag)	Q14314 (V205-P439)	≥95%
HY-P700987	FGL2 Protein, Human (Biotinylated, HEK293, His-Avi, Flag)	Q14314 (V205-P439)	≥95%
HY-P701078	FGL2 Protein, Human (HEK293, hFc-Flag)	Q14314 (V205-P439)	≥95%

Related Diseases

Diseases

Alias

Viral Hepatitis

Animal Viral Hepatitis	Hepatitis, Viral, Animal
Human Viral Hepatitis	Viral Hepatitis With Hepatic Coma

Hepatitis B

Chronic Hepatitis B	Hepatitis B Infection
Serum Hepatitis	HBV
Hepatitis B Chronic	Hbv, Susceptibility To
Hepatitis B, Chronic	Chronic Hepatitis B Without Delta Agent
Chronic Hbv - [Hepatitis B Virus] Infection	Hepatitis B Nos
Chronic Type B Viral Hepatitis	Hep B Nos

Ileum Cancer

Ileal Neoplasm	Malignant Neoplasm Of Ileum
Ileal Cancer	Ileal Neoplasms

Autoimmune Glomerulonephritis

Pontocerebellar Hypoplasia, Type 3

Pontocerebellar Hypoplasia Type 3	Cerebellar Atrophy With Progressive Microcephaly
PCH3	Clam
Pch With Optic Atrophy	Pontocerebellar Hypoplasia 3
Hypoplasia, Pontocerebellar, Type 3

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04928	FGL2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	FGL2	VGNC	VGNC:80044
Rattus norvegicus	FGL2	RGD	RGD:620170
Mus musculus	FGL2	MGD	MGI:103266
Macaca mulatta	FGL2	VGNC	VGNC:72657
Bos taurus	FGL2	VGNC	VGNC:28993
Canis familiaris	FGL2	VGNC	VGNC:40865
Macaca fascicularis	FGL2	NCBI	NCBI:102123631
Others	FGL2	NCBI

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