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  4. FGL-2
  5. FGL2 Protein, Human (HEK293, His-Avi, Flag)

FGL2 Protein, Human (HEK293, His-Avi, Flag)

Cat. No.: HY-P700721
Handling Instructions

FGL2 protein is involved in immune responses specific to mucosal tissues, regulating physiologic lymphocyte functions. It forms disulfide-linked homotetramers, indicating its quaternary structure. Studying how FGL2 influences lymphocyte functions and its homotetrameric organization can provide insights into its role in mucosal immunity and immune system regulation. FGL2 Protein, Human (HEK293, His-Avi, Flag) is the recombinant human-derived FGL2 protein, expressed by HEK293 , with C-Avi, N-His, N-Flag labeled tag. The total length of FGL2 Protein, Human (HEK293, His-Avi, Flag) is 235 a.a., with molecular weight of 40-50 kDa.

For research use only. We do not sell to patients.

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Description

FGL2 protein is involved in immune responses specific to mucosal tissues, regulating physiologic lymphocyte functions. It forms disulfide-linked homotetramers, indicating its quaternary structure. Studying how FGL2 influences lymphocyte functions and its homotetrameric organization can provide insights into its role in mucosal immunity and immune system regulation. FGL2 Protein, Human (HEK293, His-Avi, Flag) is the recombinant human-derived FGL2 protein, expressed by HEK293 , with C-Avi, N-His, N-Flag labeled tag. The total length of FGL2 Protein, Human (HEK293, His-Avi, Flag) is 235 a.a., with molecular weight of 40-50 kDa.

Background

The FGL2 protein appears to play a role in physiologic lymphocyte functions at mucosal sites, suggesting its involvement in immune responses specific to mucosal tissues. Its potential contribution to lymphocyte functions implies a role in the regulation of immune activities at these specialized sites. Structurally, FGL2 forms homotetramers that are disulfide-linked, highlighting its quaternary structure. Further exploration into the specific mechanisms by which FGL2 influences physiologic lymphocyte functions at mucosal sites and the functional consequences of its homotetrameric organization could provide valuable insights into its role in mucosal immunity and immune system regulation.

Species

Human

Source

HEK293

Tag

N-His;N-Flag;N-Avi

Accession

Q14314 (V205-P439)

Gene ID
Synonyms
Fibroleukin; pT49; FGL2; fibrinogen-like 2;
Molecular Weight

40-50 kDa

Purity

Greater than 95% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

FGL2 Protein, Human (HEK293, His-Avi, Flag) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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FGL2 Protein, Human (HEK293, His-Avi, Flag)
Cat. No.:
HY-P700721
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