C1QL1 - complement C1q like 1 Gene

Homo sapiens

Also known as CRF; C1QRF; CTRP14; C1QTNF14

Gene ID: 10882 | Gene type: protein coding

About C1QL1

Cytogenetic location: 17q21.31 Genomic coordinates (GRCh38): 17:44,959,693-44,968,303 (from NCBI)

This gene has 1 transcript (splice variant), 179 orthologues and 23 paralogues. Biased expression in brain (RPKM 10.8), kidney (RPKM 1.7) and 4 other tissues.

Summary

Predicted to enable signaling receptor binding activity. Predicted to act upstream of or within maintenance of synapse structure; motor learning; and neuron remodeling. Predicted to be located in several cellular components, including climbing fiber; presynapse; and synaptic cleft. Predicted to be part of collagen trimer. [provided by Alliance of Genome Resources, Apr 2022]

C1QL1 Products(1)

mRNA	Protein	Name
NM_006688.5	NP_006679.1	C1q-related factor precursor

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	19666007	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

C1QL1 Protein Structure

Collagen

C1q

0
100
200
258 a.a.

Protein Preferred Names

Protein Names

C1q-related factor

C1q and tumor necrosis factor-related protein 14

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01722	C1QL1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	C1QL1	MGD	MGI:1344400
Bos taurus	C1QL1	VGNC	VGNC:26620
Macaca mulatta	C1QL1	VGNC	VGNC:70372
Rattus norvegicus	C1QL1	RGD	RGD:1306039
Felis catus	C1QL1	VGNC	VGNC:98773
Canis familiaris	C1QL1	VGNC	VGNC:38579

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