2. Gene
  3. Mpi - mannose phosphate isomerase Gene

Mpi - mannose phosphate isomerase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Mpi1; Mpi-1; 1110002E17Rik

Gene ID: 110119 | Gene type: protein coding

About Mpi

Summary

Enables mannose-6-phosphate isomerase activity. Acts upstream of or within GDP-mannose biosynthetic process and mannose to fructose-6-phosphate metabolic process. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in carbohydrate metabolic disorder and congenital disorder of glycosylation Ib. Orthologous to human MPI (mannose phosphate isomerase). [provided by Alliance of Genome Resources, Apr 2022]

Mpi Products(1)

mRNA Protein Name
NM_025837.2 NP_080113.1 mannose-6-phosphate isomerase
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables mannose-6-phosphate isomerase activity IDA
IDA: Inferred from direct assay
204065 MGI
enables mannose-6-phosphate isomerase activity IMP
IMP: Inferred from mutant phenotype
16339137 MGI
Biological Process GO Annotation Evidence Reference Source
involved in GDP-mannose biosynthetic process from glucose IMP
IMP: Inferred from mutant phenotype
24218558 MGI
acts upstream of or within mannose to fructose-6-phosphate catabolic process IMP
IMP: Inferred from mutant phenotype
16339137 MGI
Cellular Component GO Annotation Evidence Reference Source
is active in cytosol IDA
IDA: Inferred from direct assay
12122025 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mannose-6-phosphate isomerase

PMI

mannose phosphate isomerase 1

phosphohexomutase

phosphomannose isomerase

Related Agents

Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-147416 Vipoglanstat Inhibitor 99.74% Phase 2
Pre-clinical Phase
Bioactive Molecules (9)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-112945 MLS0315771 Inhibitor 99.46% Unkown
HY-12660 MPI-0479605 99.51% Unkown
HY-113957 MPI_5a Inhibitor ≥99.0% Unkown
HY-155813 MPI60 Inhibitor / Unkown
HY-129715 MPI-0441138 Inducer / Unkown
HY-RS08614 MPI Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-158763 MPI8 Inhibitor / Unkown
HY-163627 SARS-CoV-2 Mpro-IN-19 Inhibitor / Unkown
HY-163628 SARS-CoV-2 Mpro-IN-20 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mpi NCBI NCBI:4351
Macaca fascicularis Mpi NCBI NCBI:101867469
Rattus norvegicus Mpi NCBI NCBI:300741