2. Gene
  3. LILRA1 - leukocyte immunoglobulin like receptor A1 Gene

LILRA1 - leukocyte immunoglobulin like receptor A1 Gene

  • Gene
  • Protein
  • Agent
Homo sapiens

Also known as LIR6; CD85I; LIR-6

Gene ID: 11024 | Gene type: protein coding

About LILRA1

Cytogenetic location: 19q13.42 Genomic coordinates (GRCh38): 19:54,593,632-54,602,381 (from NCBI)

This gene has 5 transcripts (splice variants), 1 gene allele, 303 orthologues and 25 paralogues. Biased expression in appendix (RPKM 8.6), spleen (RPKM 6.8) and 6 other tissues.

Summary

This gene encodes an activating member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein is predominantly expressed in B cells, interacts with major histocompatibility complex class I ligands, and contributes to the regulation of immune responses. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]

LILRA1 Products(3)

mRNA Protein Name
NM_001278318.2 NP_001265247.1 leukocyte immunoglobulin-like receptor subfamily A member 1 isoform 2 precursor
NM_001278319.1 NP_001265248.1 leukocyte immunoglobulin-like receptor subfamily A member 1 isoform 3 precursor
NM_006863.4 NP_006854.1 leukocyte immunoglobulin-like receptor subfamily A member 1 isoform 1 precursor

LILRA1 Protein Structure

Ig_2

Ig_2: Immunoglobulin domain (28 - 118)

Ig_3

Ig_3: Immunoglobulin domain (124 - 199)

Ig_2

Ig_2: Immunoglobulin domain (225 - 317)

Ig_3

Ig_3: Immunoglobulin domain (325 - 400)

  • 0
  • 100
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  • 400
  • 489 a.a.
Protein Preferred Names Protein Names

leukocyte immunoglobulin-like receptor subfamily A member 1

CD85 antigen-like family member I

Recombinant LILRA1 Proteins

Cat. No. Product Name Accession Purity
HY-P77440 LILRA1/LIR-6/CD85i Protein, Human (HEK293, His) O75019-1 (P17-N461) ≥95%
HY-P78169 LILRA1/LIR-6/CD85i Protein, Human (Biotinylated, HEK293, His-Avi) O75019-1 (P17-N461) ≥95%
HY-P78479 LILRA1/LIR-6/CD85i Protein, Human (HEK293, His-Avi) O75019-1 (P17-N461) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07645 LILRA1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown