PDAP1 - PDGFA associated protein 1 Gene

Homo sapiens

Also known as PAP; PAP1; HASPP28

Gene ID: 11333 | Gene type: protein coding

About PDAP1

Cytogenetic location: 7q22.1 Genomic coordinates (GRCh38): 7:99,394,673-99,408,597 (from NCBI)

This gene has 5 transcripts (splice variants) and 187 orthologues. Ubiquitous expression in fat (RPKM 24.9), colon (RPKM 23.3) and 25 other tissues.

Summary

The protein encoded by this gene is a phosphoprotein that may upregulate the PDGFA-stimulated growth of fibroblasts and also downregulate the mitogenicity of PDGFB. The encoded protein in rodents has been shown to bind PDGFA with a low affinity. [provided by RefSeq, Dec 2010]

PDAP1 Products(1)

mRNA	Protein	Name
NM_014891.7	NP_055706.1	28 kDa heat- and acid-stable phosphoprotein

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PDAP1 Protein Structure

PP28

0
100
181 a.a.

Protein Preferred Names

Protein Names

28 kDa heat- and acid-stable phosphoprotein

PDGF-associated protein

Recombinant PDAP1 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P71186	PAP Protein, Human (His)	Q13442 (M1-K181)	≥95%

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10183	PDAP1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	PDAP1	VGNC	VGNC:32655
Felis catus	PDAP1	VGNC	VGNC:64076
Canis familiaris	PDAP1	VGNC	VGNC:44332
Rattus norvegicus	PDAP1	RGD	RGD:620442
Macaca mulatta	PDAP1	VGNC	VGNC:75604
Mus musculus	PDAP1	MGD	MGI:2448536
Others	PDAP1	NCBI

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