EXOC3 - exocyst complex component 3 Gene

Homo sapiens

Also known as SEC6; Sec6p; SEC6L1

Gene ID: 11336 | Gene type: protein coding

About EXOC3

Cytogenetic location: 5p15.33 Genomic coordinates (GRCh38): 5:443,176-467,290 (from NCBI)

This gene has 10 transcripts (splice variants), 212 orthologues and 4 paralogues. Ubiquitous expression in colon (RPKM 23.5), kidney (RPKM 21.1) and 25 other tissues.

Summary

The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. [provided by RefSeq, Jul 2008]

EXOC3 Products(1)

mRNA	Protein	Name
NM_007277.5	NP_009208.2	exocyst complex component 3

EXOC3 Protein Structure

Sec6

0
200
400
600
745 a.a.

Protein Preferred Names

Protein Names

exocyst complex component 3

SEC6-like 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04589	EXOC3 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	EXOC3	VGNC	VGNC:72409
Canis familiaris	EXOC3	VGNC	VGNC:103674
Mus musculus	EXOC3	MGD	MGI:2443972
Bos taurus	EXOC3	VGNC	VGNC:28645
Felis catus	EXOC3	VGNC	VGNC:61999
Rattus norvegicus	EXOC3	RGD	RGD:621790

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