ZIM3 - zinc finger imprinted 3 Gene

Homo sapiens

Also known as ZNF264; ZNF657

Gene ID: 114026 | Gene type: protein coding

About ZIM3

This gene has 1 transcript (splice variant), 28 orthologues and 174 paralogues. Low expression observed in reference dataset.

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

ZIM3 Products(1)

mRNA	Protein	Name
NM_052882.1	NP_443114.1	zinc finger imprinted 3

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZIM3 Protein Structure

KRAB

zf-H2C2_2

0
100
200
300
400
472 a.a.

Protein Preferred Names

Protein Names

zinc finger imprinted 3

Zinc finger protein 264

ZIM3 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	ZIM3	Q96PE6	RING1	Homo sapiens	Q06587	Y2H Array	32296183
Intra	ZIM3	Q96PE6	RING1	Homo sapiens	Q06587	Y2H Prey Pooling	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS16080	ZIM3 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	ZIM3	VGNC	VGNC:84910
Rattus norvegicus	ZIM3	RGD	RGD:6499280

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