Acp5 - acid phosphatase 5, tartrate resistant Gene

Mus musculus

Also known as TRAP; TRACP

Gene ID: 11433 | Gene type: protein coding

About Acp5

Summary

Enables Acid Phosphatase activity. Acts upstream of or within several processes, including bone resorption; negative regulation of cytokine production; and response to bacterium. Located in lysosome. Is expressed in several structures, including alimentary system; limb; liver; skeleton; and skin. Orthologous to human ACP5 (Acid Phosphatase 5, tartrate resistant). [provided by Alliance of Genome Resources, Apr 2022]

Acp5 Products(3)

mRNA	Protein	Name
NM_001102404.1	NP_001095874.1	tartrate-resistant acid phosphatase type 5 precursor
NM_001102405.1	NP_001095875.1	tartrate-resistant acid phosphatase type 5 precursor
NM_007388.3	NP_031414.1	tartrate-resistant acid phosphatase type 5 precursor

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables acid phosphatase activity	IDA IDA: Inferred from direct assay	9308894	MGI
enables acid phosphatase activity	IMP IMP: Inferred from mutant phenotype	8898228	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within bone morphogenesis	IMP IMP: Inferred from mutant phenotype	8898228	MGI
acts upstream of or within bone resorption	IMP IMP: Inferred from mutant phenotype	8898228	MGI
acts upstream of or within defense response to Gram-positive bacterium	IMP IMP: Inferred from mutant phenotype	11168643	MGI
acts upstream of or within dephosphorylation	IDA IDA: Inferred from direct assay	9308894	MGI
acts upstream of interleukin-1 beta production	IMP IMP: Inferred from mutant phenotype	11168643	MGI
acts upstream of interleukin-12 production	IMP IMP: Inferred from mutant phenotype	11168643	MGI
acts upstream of macrophage cytokine production	IMP IMP: Inferred from mutant phenotype	11168643	MGI
acts upstream of or within negative regulation of inflammatory response	IMP IMP: Inferred from mutant phenotype	11168643	MGI
acts upstream of or within negative regulation of interleukin-1 beta production	IMP IMP: Inferred from mutant phenotype	11168643	MGI
acts upstream of or within negative regulation of interleukin-12 production	IMP IMP: Inferred from mutant phenotype	11168643	MGI
acts upstream of or within negative regulation of macrophage cytokine production	IMP IMP: Inferred from mutant phenotype	11168643	MGI
acts upstream of or within negative regulation of nitric oxide biosynthetic process	IMP IMP: Inferred from mutant phenotype	11168643	MGI
acts upstream of or within negative regulation of superoxide anion generation	IMP IMP: Inferred from mutant phenotype	11168643	MGI
acts upstream of or within negative regulation of tumor necrosis factor production	IMP IMP: Inferred from mutant phenotype	11168643	MGI
acts upstream of nitric oxide biosynthetic process	IMP IMP: Inferred from mutant phenotype	11168643	MGI
acts upstream of or within response to cytokine	IDA IDA: Inferred from direct assay	8200916	MGI
acts upstream of or within response to lipopolysaccharide	IMP IMP: Inferred from mutant phenotype	11168643	MGI
acts upstream of superoxide anion generation	IMP IMP: Inferred from mutant phenotype	11168643	MGI
acts upstream of tumor necrosis factor production	IMP IMP: Inferred from mutant phenotype	11168643	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in lysosome	IDA IDA: Inferred from direct assay	11168643	MGI
located in lysosome	IMP IMP: Inferred from mutant phenotype	11731469	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

tartrate-resistant acid phosphatase type 5

TR-AP	acid phosphatase type V
tartrate-resistant acid ATPase	trATPase
type 5 acid phosphatase

Recombinant Acp5 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P75540	ACP5 Protein, Mouse (HEK293, His)	Q05117 (A23-P327)	≥95%

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-124663	CBK289001	Inhibitor	/	Unkown
HY-RS00190	ACP5 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-138869	AubipyOMe		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Acp5	NCBI	NCBI:54

Name
Email *

	Sorry, but the email address you supplied was invalid.