2. Gene
  3. Ak1 - adenylate kinase 1 Gene

Ak1 - adenylate kinase 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Ak-1; B430205N08Rik

Gene ID: 11636 | Gene type: protein coding

About Ak1

Summary

Enables adenylate kinase activity. Acts upstream of or within regulation of G1/S transition of mitotic cell cycle. Located in cytoplasm; outer dense fiber; and plasma membrane. Is expressed in several structures, including heart; lung; metanephros; nervous system; and nose. Human ortholog(s) of this gene implicated in congenital nonspherocytic hemolytic anemia and hemolytic anemia. Orthologous to human AK1 (adenylate kinase 1). [provided by Alliance of Genome Resources, Apr 2022]

Ak1 Products(4)

mRNA Protein Name
NM_001198790.1 NP_001185719.1 adenylate kinase isoenzyme 1 isoform 2
NM_001198791.1 NP_001185720.1 adenylate kinase isoenzyme 1 isoform 2
NM_001198792.1 NP_001185721.1 adenylate kinase isoenzyme 1 isoform 2
NM_021515.3 NP_067490.1 adenylate kinase isoenzyme 1 isoform 1
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables adenylate kinase activity IDA
IDA: Inferred from direct assay
198184 MGI
Cellular Component GO Annotation Evidence Reference Source
located in outer dense fiber IDA
IDA: Inferred from direct assay
16790685 MGI
located in sperm flagellum IDA
IDA: Inferred from direct assay
16790685 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

adenylate kinase isoenzyme 1

cytosolic adenylate kinase

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-101465 AK-1 Inhibitor 99.97% Unkown
HY-RS00505 AK1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS04242 EIF2AK1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ak1 NCBI NCBI:203
Macaca fascicularis Ak1 NCBI NCBI:101867187
Rattus norvegicus Ak1 NCBI NCBI:24183