2. Gene
  3. Arf1 - ADP-ribosylation factor 1 Gene

Arf1 - ADP-ribosylation factor 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus
Gene ID: 11840 | Gene type: protein coding

About Arf1

Summary

Enables GTP binding activity and magnesium ion binding activity. Involved in mitotic cleavage furrow ingression. Acts upstream of or within vesicle-mediated transport. Located in Golgi apparatus; cytosol; and sarcomere. Part of protein-containing complex. Is expressed in several structures, including cardiovascular system; genitourinary system; gut; integumental system; and nervous system. Human ortholog(s) of this gene implicated in periventricular nodular heterotopia. Orthologous to human ARF1 (ADP ribosylation factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Arf1 Products(2)

mRNA Protein Name
NM_001130408.2 NP_001123880.1 ADP-ribosylation factor 1
NM_007476.4 NP_031502.1 ADP-ribosylation factor 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables GTP binding IMP
IMP: Inferred from mutant phenotype
12679809 MGI
enables magnesium ion binding IMP
IMP: Inferred from mutant phenotype
12679809 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
12679809 MGI
Biological Process GO Annotation Evidence Reference Source
involved in mitotic cleavage furrow ingression IGI
IGI: Inferred from genetic interaction
27535433 MGI
acts upstream of or within vesicle-mediated transport IDA
IDA: Inferred from direct assay
14728599 MGI
Cellular Component GO Annotation Evidence Reference Source
located in Golgi apparatus IDA
IDA: Inferred from direct assay
8947846 MGI
located in cytosol IDA
IDA: Inferred from direct assay
14728599 MGI
located in endomembrane system IDA
IDA: Inferred from direct assay
14728599 MGI
part of protein-containing complex IMP
IMP: Inferred from mutant phenotype
12679809 MGI
located in sarcomere IDA
IDA: Inferred from direct assay
14728599 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ADP-ribosylation factor 1

Arf1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Cross
Arf1 P84078 ARHGAP21 Homo sapiens Q5T5U3
Cosedimentation
17347647
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-112473 NAV-2729 Inhibitor 98.57% Unkown
HY-P10157 ARF(1-22) / Unkown
HY-RS00894 ARF1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-P10658 ARF1 (2-17) Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Arf1 NCBI NCBI:375