MUCL1 - mucin like 1 Gene

Homo sapiens

Also known as SBEM

Gene ID: 118430 | Gene type: protein coding

About MUCL1

Cytogenetic location: 12q13.2 Genomic coordinates (GRCh38): 12:54,830,681-54,858,387 (from NCBI)

This gene has 5 transcripts (splice variants) and 9 orthologues. Biased expression in salivary gland (RPKM 37.1), skin (RPKM 4.7) and 1 other tissue.

Summary

Predicted to be located in Golgi lumen and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

MUCL1 Products(1)

mRNA	Protein	Name
NM_058173.3	NP_477521.1	mucin-like protein 1 precursor

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

mucin-like protein 1

small breast epithelial mucin

MUCL1 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	MUCL1	Q96DR8	ARL13B	Homo sapiens	Q3SXY8	Y2H Array	32296183
Intra	MUCL1	Q96DR8	ARL13B	Homo sapiens	Q3SXY8	Y2H Prey Pooling	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant MUCL1 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P77091	MUCL1 Protein, Human (HEK293, His)	Q96DR8 (N21-P90)	≥95%

Related Diseases

Diseases

Alias

Homocystinuria-Megaloblastic Anemia, Cblg Complementation Type

Methylcobalamin Deficiency, Cblg Type	HMAG
Methionine Synthase Deficiency	Methylcobalamin Deficiency Type Cblg
Homocystinuria-Megaloblastic Anemia Due To Defect In Cobalamin Metabolism, Cblg Complementation Type	Homocystinuria-Megaloblastic Anemia Cblg Type
Homocystinuria-Megaloblastic Anemia Due To Defect In Cobalamin Metabolism Cblg Complementation Type	Methylcobalamin Deficiency Cbl G Type
Homocystinuria Due To Defect In Methylation Cbl G	Cblg
Functional Methionine Synthase Deficiency Type Cblg	Methylcobalamin Deficiency Cblg Type
Arakawa Syndrome 2

Arthrogryposis, Distal, Type 1c

DA1C	Distal Arthrogryposis Type 1c
Arthrogryposis, Distal, 1c

Breast Cancer

Breast Carcinoma	Male Breast Cancer
Breast Cancer, Familial	Malignant Neoplasm Of Breast
Breast Cancer, Susceptibility To	Breast Cancer, Early-Onset
Malignant Tumor Of Breast	Carcinoma Of Male Breast
Breast Cancer, Invasive Ductal	Breast Cancer, Protection Against
Breast Cancer, Somatic	Breast Cancer, Male
Breast Cancer, Lobular, Somatic	Breast Tumor
Mammary Cancer	Mammary Tumor
Malignant Neoplasm Of Male Breast	Mammary Carcinoma
Male Breast Carcinoma	Familial Cancer Of Breast
Invasive Ductal Breast Carcinoma	Breast Cancer Susceptibility
Breast Cancer, Male, Susceptibility To	Breast Cancer, Early-Onset, Susceptibility To
Malignant Tumor Of The Breast	Mammary Neoplasm
Primary Breast Cancer	Neoplasm Of Male Breast
Carcinoma Of Breast	Breast Cancer In Men
Familial Breast Cancer	Cancer Of Breast
BC	Breast Cancer Familial
Breast Cancer Familial Male	Breast Cancer, Familial Male
Breast Male Carcinoma	Breast Neoplasms
Breast Neoplasms, Male	Mammary Tumors
Mammary Carcinomas	Cancer, Breast
Cancer, Breast, Susceptibility	Invasive Breast Ductal Carcinoma
Breast Neoplasm	Susceptibility To Breast Cancer
Mammary Neoplasms	Animal Mammary Neoplasms
Primary Malignant Neoplasm Of Breast	Infiltrating Ductal Carcinoma Of Breast
Infiltrating Duct Carcinoma Of Unspecified Site	Infiltrating Ductular Carcinoma Of Unspecified Site
Invasive Breast Carcinoma Of No Special Type	Microinvasive Carcinoma Of Breast
Carcinoma With Apocrine Differentiation

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08849	MUCL1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

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