2. Gene
  3. Ccne1 - cyclin E1 Gene

Ccne1 - cyclin E1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as CycE1

Gene ID: 12447 | Gene type: protein coding

About Ccne1

Summary

Enables cyclin-dependent protein serine/threonine kinase regulator activity; kinase activity; and protein kinase binding activity. Acts upstream of or within several processes, including DNA metabolic process; homologous chromosome pairing at meiosis; and negative regulation of transcription by RNA polymerase II. Located in nucleus. Part of cyclin E1-CDK2 complex. Is expressed in several structures, including brain; early conceptus; embryo ectoderm; eye; and spinal cord. Human ortholog(s) of this gene implicated in breast adenocarcinoma. Orthologous to human CCNE1 (cyclin E1). [provided by Alliance of Genome Resources, Apr 2022]

Ccne1 Products(1)

mRNA Protein Name
NM_007633.2 NP_031659.2 G1/S-specific cyclin-E1
Protein Preferred Names Protein Names

G1/S-specific cyclin-E1

Recombinant Ccne1 Proteins

Cat. No. Product Name Accession Purity
HY-P72964 Cyclin E Protein, Mouse (sf9, His-GST) Q61457 (M1-E408) ≥95%

Related Agents

Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-145817A lunresertib Inhibitor 99.90% Phase 2
Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-160701 BLU-222 99.02% Unkown
HY-162255 CDK2-IN-23 Inhibitor 99.22% Unkown
HY-RS02127 CCNE1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-161463 CDK2-IN-28 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ccne1 NCBI NCBI:898