2. Gene
  3. Cd1d2 - CD1d2 antigen Gene

Cd1d2 - CD1d2 antigen Gene

  • Gene
  • Protein
Mus musculus

Also known as Cd1b; CD1.2; Ly-38

Gene ID: 12480 | Gene type: protein coding

About Cd1d2

Summary

This gene encodes a MHC class I-like molecule involved in the presentation of lipid antigens to T cells, and is involved in the activation of Natural Killer T (NKT) cells. The gene is highly similar to the CD1d1 antigen gene, which is located adjacent to this gene in a tail-to-tail fashion. This gene contains a frameshift and does not produce a functional product in the C57BL/6 strain. Alternatively splice transcript variants encoding different isoforms have been found in non-C57BL/6 strains. [provided by RefSeq, Jan 2014]

Cd1d2 Products(2)

mRNA Protein Name
NM_001289449.1 NP_001276378.1 antigen-presenting glycoprotein CD1d2 isoform 2 precursor
NM_007640.2 NP_031666.2 antigen-presenting glycoprotein CD1d2 isoform 1 precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within positive regulation of NK T cell activation IDA
IDA: Inferred from direct assay
10201995 MGI
acts upstream of or within positive regulation of T cell mediated cytotoxicity IDA
IDA: Inferred from direct assay
10201995 MGI
acts upstream of or within positive regulation of interleukin-2 production IDA
IDA: Inferred from direct assay
10201995 MGI
acts upstream of or within positive regulation of interleukin-4 production IDA
IDA: Inferred from direct assay
10201995 MGI
Cellular Component GO Annotation Evidence Reference Source
located in external side of plasma membrane IDA
IDA: Inferred from direct assay
10201995 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

antigen-presenting glycoprotein CD1d2

T-cell surface glycoprotein CD1d2

Recombinant Cd1d2 Proteins

Cat. No. Product Name Accession Purity
HY-P76779 CD1D2-B2M Heterodimer Protein, Mouse (HEK293, His) P11610 (Q22-G305)&P01887 (I21-M119) ≥95%