Entpd2 - ectonucleoside triphosphate diphosphohydrolase 2 Gene

Mus musculus

Also known as Cd39l1; NTPDase2

Gene ID: 12496 | Gene type: protein coding

About Entpd2

Summary

Enables nucleoside-diphosphatase activity and nucleoside-triphosphatase activity. Acts upstream of or within G protein-coupled receptor signaling pathway; platelet activation; and purine ribonucleoside diphosphate catabolic process. Located in basement membrane and plasma membrane. Is expressed in nervous system. Human ortholog(s) of this gene implicated in high grade glioma. Orthologous to human ENTPD2 (ectonucleoside triphosphate diphosphohydrolase 2). [provided by Alliance of Genome Resources, Apr 2022]

Entpd2 Products(1)

mRNA	Protein	Name
NM_009849.2	NP_033979.2	ectonucleoside triphosphate diphosphohydrolase 2 precursor

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables nucleoside diphosphate phosphatase activity	IDA IDA: Inferred from direct assay	11929769	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	11591653	MGI
enables ribonucleoside triphosphate phosphatase activity	IDA IDA: Inferred from direct assay	11929769	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within G protein-coupled receptor signaling pathway	IDA IDA: Inferred from direct assay	11929769	MGI
acts upstream of or within platelet activation	IDA IDA: Inferred from direct assay	11929769	MGI
acts upstream of or within purine ribonucleoside diphosphate catabolic process	IDA IDA: Inferred from direct assay	11929769	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in basement membrane	IDA IDA: Inferred from direct assay	11929769	MGI
located in plasma membrane	IDA IDA: Inferred from direct assay	23010799	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

ectonucleoside triphosphate diphosphohydrolase 2

CD39 antigen-like 1	NTPDase 2
ecto-ATP diphosphohydrolase 2	ecto-ATPDase 2
ecto-ATPase 2

Recombinant Entpd2 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P72729	CD39L1/ENTPD2 Protein, Mouse (HEK293, His)	O55026 (C26-S462)	≥95%

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04396	ENTPD2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Entpd2	NCBI	NCBI:954

Name
Email *

	Sorry, but the email address you supplied was invalid.