ENTPD2 - ectonucleoside triphosphate diphosphohydrolase 2 Gene

Homo sapiens

Also known as CD39L1; NTPDase-2

Gene ID: 954 | Gene type: protein coding

About ENTPD2

Cytogenetic location: 9q34.3 Genomic coordinates (GRCh38): 9:137,048,107-137,054,061 (from NCBI)

This gene has 4 transcripts (splice variants), 250 orthologues and 7 paralogues. Broad expression in duodenum (RPKM 4.7), prostate (RPKM 4.6) and 17 other tissues.

Summary

The protein encoded by this gene is the type 2 Enzyme of the ecto-nucleoside triphosphate diphosphohydrolase family (E-NTPDase). E-NTPDases are a family of ecto-nucleosidases that hydrolyze 5'-triphosphates. This ecto-ATPase is an integral membrane protein. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]

ENTPD2 Products(2)

mRNA	Protein	Name
NM_001246.4	NP_001237.1	ectonucleoside triphosphate diphosphohydrolase 2 isoform 2
NM_203468.3	NP_982293.1	ectonucleoside triphosphate diphosphohydrolase 2 isoform 1

ENTPD2 Protein Structure

GDA1_CD39

0
100
200
300
400
495 a.a.

Protein Preferred Names

Protein Names

ectonucleoside triphosphate diphosphohydrolase 2

CD39 antigen-like 1

Recombinant ENTPD2 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P72730	CD39L1/ENTPD2 Protein, Human (HEK293, His)	Q9Y5L3 (T29-D460)	≥95%
HY-P76903	CD39L1/ENTPD2 Protein, Human (sf9, His)	Q9Y5L3 (T29-D460)	≥95%

Related Diseases

Diseases

Alias

Cholera

Vibrio Cholerae Infection	Cholera - Vibrio Cholerae
Cholera Due To Vibrio Cholerae	Vibrio Cholerae
Cholera Syndrome	Asiatic Cholera
Epidemic Cholera

Jejunoileitis

Megalencephalic Leukoencephalopathy With Subcortical Cysts 1

Van Der Knaap Disease	Leukoencephalopathy With Swelling And Cysts
MLC1	Vacuolating Megalencephalic Leukoencephalopathy With Subcortical Cysts
Lvm	Vl
Leukoencephalopathy, Megalencephalic, With Subcortical Cysts, 1	Leukoencephalopathy, Megalencephalic, With Subcortical Cysts, Type 1
Megalencephalic Leukoencephalopathy With Subcortical Cysts

Palmoplantar Keratoderma And Congenital Alopecia 1

Autosomal Dominant Palmoplantar Keratoderma And Congenital Alopecia	PPKCA1
Keratoderma-Hypotrichosis-Leukonychia Totalis Syndrome	Autosomal Dominant Palmoplantar Hyperkeratosis And Congenital Alopecia
Palmoplantar Keratoderma And Congenital Alopecia, Stevanovic Type	Ppk-Ca, Stevanovic Type
Ppkca, Stevanovic Type	Palmoplantar Keratoderma With Congenital Alopecia
Ppkca Stevanovic Type	Alopecia Congenita With Hyperkeratosis Of The Palms And Soles
Alopecia Congenita Keratosis Palmoplantaris	Keratoderma, Palmoplantar, With Congenital Alopecia, Type 1

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04396	ENTPD2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	ENTPD2	RGD	RGD:69266
Bos taurus	ENTPD2	VGNC	VGNC:28509
Mus musculus	ENTPD2	MGD	MGI:1096863
Felis catus	ENTPD2	VGNC	VGNC:61879
Macaca mulatta	ENTPD2	VGNC	VGNC:72225
Canis familiaris	ENTPD2	VGNC	VGNC:40381
Others	ENTPD2	NCBI

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