Entpd5 - ectonucleoside triphosphate diphosphohydrolase 5 Gene

Mus musculus

Also known as Pcph; Cd39l4; mNTPase; NTPDase5; ER-UDPase; NTPDase-5

Gene ID: 12499 | Gene type: protein coding

About Entpd5

Summary

Enables guanosine-diphosphatase activity and uridine-diphosphatase activity. Involved in several processes, including positive regulation of glycolytic process; protein N-linked glycosylation; and regulation of phosphatidylinositol 3-kinase signaling. Located in endoplasmic reticulum. Is expressed in several structures, including genitourinary system; gut; hemolymphoid system gland; liver; and nose. Orthologous to human ENTPD5 (ectonucleoside triphosphate diphosphohydrolase 5 (inactive)). [provided by Alliance of Genome Resources, Apr 2022]

Entpd5 Products(4)

mRNA	Protein	Name
NM_001026214.2	NP_001021385.1	ectonucleoside triphosphate diphosphohydrolase 5 isoform b precursor
NM_001286049.1	NP_001272978.1	ectonucleoside triphosphate diphosphohydrolase 5 isoform b precursor
NM_001286058.1	NP_001272987.1	ectonucleoside triphosphate diphosphohydrolase 5 isoform b precursor
NM_007647.3	NP_031673.2	ectonucleoside triphosphate diphosphohydrolase 5 isoform a

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables GDP phosphatase activity	IDA IDA: Inferred from direct assay	21074248	MGI
enables UDP phosphatase activity	IDA IDA: Inferred from direct assay	10369669	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of positive effect 'de novo' post-translational protein folding	IMP IMP: Inferred from mutant phenotype	21074248	MGI
involved in UDP catabolic process	IDA IDA: Inferred from direct assay	10369669	MGI
acts upstream of positive effect UDP-glucose metabolic process	IMP IMP: Inferred from mutant phenotype	21074248	MGI
acts upstream of positive effect protein N-linked glycosylation	IMP IMP: Inferred from mutant phenotype	21074248	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
NOT located in Golgi apparatus	IDA IDA: Inferred from direct assay	10369669	MGI
located in endoplasmic reticulum	IDA IDA: Inferred from direct assay	21074248	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

ectonucleoside triphosphate diphosphohydrolase 5

CD39 antigen-like 4	GDPase ENTPD5
NTPDase 5	UDPase ENTPD5
guanosine-diphosphatase ENTPD5	nucleoside diphosphatase
uridine-diphosphatase ENTPD5

Recombinant Entpd5 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P76317	CD39L4/ENTPD5 Protein, Mouse (sf9, His)	Q9WUZ9 (T19-S427)	≥95%

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04399	ENTPD5 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Entpd5	NCBI	NCBI:957

Name
Email *

	Sorry, but the email address you supplied was invalid.