Cd3g - CD3 antigen, gamma polypeptide Gene

Mus musculus

Also known as T3g; Ctg3; Ctg-3

Gene ID: 12502 | Gene type: protein coding

About Cd3g

Summary

Predicted to enable identical protein binding activity and transmembrane signaling receptor activity. Predicted to be involved in several processes, including positive thymic T cell selection; protein transport; and regulation of lymphocyte apoptotic process. Predicted to act upstream of or within adaptive immune response. Part of alpha-beta T cell receptor complex. Human ortholog(s) of this gene implicated in immunodeficiency 17. Orthologous to human CD3g (CD3g molecule). [provided by Alliance of Genome Resources, Apr 2022]

Cd3g Products(1)

mRNA	Protein	Name
NM_009850.2	NP_033980.1	T-cell surface glycoprotein CD3 gamma chain precursor

Gene Ontology

Cellular Component

Cellular Component GO Annotation	Evidence	Reference	Source
part of alpha-beta T cell receptor complex	IDA IDA: Inferred from direct assay	9208839	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

T-cell surface glycoprotein CD3 gamma chain

T-cell receptor T3 gamma chain

Recombinant Cd3g Proteins

Cat. No.	Product Name	Accession	Purity
HY-P75414	CD3E-CD3G Heterodimer Protein, Mouse (HEK293, Fc)	NP_031674.1 (D23-D108)&NP_033980.1 (Q23-S116)	≥95%

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02244	CD3G Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Inhibitory Antibodies (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P990698	Umizortamig		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Cd3g	NCBI	NCBI:917
Macaca fascicularis	Cd3g	NCBI	NCBI:102134381
Macaca mulatta	Cd3g	NCBI	NCBI:705270

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