OR7D4 - olfactory receptor family 7 subfamily D member 4 Gene

Homo sapiens

Also known as OR19B; hg105; OR19-7; OR19-B; OR7D4P

Gene ID: 125958 | Gene type: protein coding

About OR7D4

Cytogenetic location: 19p13.2 Genomic coordinates (GRCh38): 19:9,210,276-9,219,589 (from NCBI)

This gene has 3 transcripts (splice variants), 180 orthologues and 130 paralogues.

Summary

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory Receptor Proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of Other organisms. [provided by RefSeq, Jul 2008]

OR7D4 Products(1)

mRNA	Protein	Name
NM_001005191.3	NP_001005191.1	olfactory receptor 7D4

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

OR7D4 Protein Structure

7tm_4

0
100
200
312 a.a.

Protein Preferred Names

Protein Names

olfactory receptor 7D4

odorant receptor family 7 subfamily D member 4 RT

OR7D4 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	OR7D4	Q8NG98	SLC10A6	Homo sapiens	Q3KNW5	Y2H Prey Pooling	32296183
Intra	OR7D4	Q8NG98	SLC10A6	Homo sapiens	Q3KNW5	Y2H Array	32296183
Intra	OR7D4	Q8NG98	UBQLN2	Homo sapiens	Q9UHD9	Y2H Prey Pooling	32296183
Intra	OR7D4	Q8NG98	UBQLN2	Homo sapiens	Q9UHD9	Validated Y2H	32296183
Intra	OR7D4	Q8NG98	UBQLN2	Homo sapiens	Q9UHD9	Y2H Array	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09821	OR7D4 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	OR7D4	RGD	RGD:1334297

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