2. Gene
  3. TMIGD2 - transmembrane and immunoglobulin domain containing 2 Gene

TMIGD2 - transmembrane and immunoglobulin domain containing 2 Gene

  • Gene
  • Protein
  • Agent
Homo sapiens

Also known as CD28H; IGPR1; IGPR-1

Gene ID: 126259 | Gene type: protein coding

About TMIGD2

Cytogenetic location: 19p13.3 Genomic coordinates (GRCh38): 19:4,292,227-4,302,389 (from NCBI)

This gene has 4 transcripts (splice variants) and 43 orthologues. Broad expression in lymph node (RPKM 1.8), spleen (RPKM 1.5) and 14 other tissues.

Summary

Enables coreceptor activity. Involved in positive regulation of T cell activation; positive regulation of angiogenesis; and positive regulation of cytokine production. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Apr 2022]

TMIGD2 Products(4)

mRNA Protein Name
NM_001169126.2 NP_001162597.1 transmembrane and immunoglobulin domain-containing protein 2 isoform 2 precursor
NM_001308232.2 NP_001295161.1 transmembrane and immunoglobulin domain-containing protein 2 isoform 3
NM_001395549.1 NP_001382478.1 transmembrane and immunoglobulin domain-containing protein 2 isoform 4 precursor
NM_144615.3 NP_653216.2 transmembrane and immunoglobulin domain-containing protein 2 isoform 1 precursor

TMIGD2 Protein Structure

Ig_2

Ig_2: Immunoglobulin domain (30 - 115)

  • 0
  • 100
  • 200
  • 282 a.a.
Protein Preferred Names Protein Names

transmembrane and immunoglobulin domain-containing protein 2

CD28 homolog

Recombinant TMIGD2 Proteins

Cat. No. Product Name Accession Purity
HY-P71370 TMIGD2 Protein, Human (HEK293, His) Q96BF3-1 (L23-G150) ≥95%
HY-P77249 TMIGD2 Protein, Human (HEK293, Fc) Q96BF3-1/NP_653216.2 (L23-G150) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14757 TMIGD2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown