2. Gene
  3. IRGQ - immunity related GTPase Q Gene

IRGQ - immunity related GTPase Q Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as IRGQ1; FKSG27

Gene ID: 126298 | Gene type: protein coding

About IRGQ

This gene has 3 transcripts (splice variants) and 88 orthologues. Ubiquitous expression in brain (RPKM 3.6), bone marrow (RPKM 3.5) and 25 other tissues.

Summary

Predicted to enable GTP binding activity. [provided by Alliance of Genome Resources, Apr 2022]

IRGQ Products(2)

mRNA Protein Name
NM_001007561.3 NP_001007562.1 immunity-related GTPase family Q protein
NM_001388309.1 NP_001375238.1 immunity-related GTPase family Q protein
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

immunity-related GTPase family Q protein

immunity-related GTPase family, Q

IRGQ Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
IRGQ Q8WZA9 MAP1LC3B Homo sapiens Q9GZQ8
Validated Y2H
32296183
Intra
IRGQ Q8WZA9 MAP1LC3B Homo sapiens Q9GZQ8
Y2H Array
32296183
Intra
IRGQ Q8WZA9 MAP1LC3B Homo sapiens Q9GZQ8
Y2H Prey Pooling
32296183
Intra
IRGQ Q8WZA9 MAP1LC3A Homo sapiens Q9H492
Y2H Prey Pooling
32296183
Intra
IRGQ Q8WZA9 MAP1LC3A Homo sapiens Q9H492
Validated Y2H
32296183
Intra
IRGQ Q8WZA9 MAP1LC3A Homo sapiens Q9H492
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06916 IRGQ Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris IRGQ VGNC VGNC:42098
Mus musculus IRGQ MGD MGI:2667176
Macaca mulatta IRGQ VGNC VGNC:73645
Rattus norvegicus IRGQ RGD RGD:1309409
Bos taurus IRGQ VGNC VGNC:30282