PRRC1 - proline rich coiled-coil 1 Gene

Homo sapiens

Gene ID: 133619 | Gene type: protein coding

About PRRC1

This gene has 6 transcripts (splice variants) and 198 orthologues. Ubiquitous expression in thyroid (RPKM 18.8), endometrium (RPKM 14.7) and 25 other tissues.

Summary

Predicted to enable identical protein binding activity and protein kinase A regulatory subunit binding activity. Predicted to be involved in activation of protein kinase A activity. Predicted to be located in Golgi apparatus. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

PRRC1 Products(2)

mRNA	Protein	Name
NM_001286808.2	NP_001273737.1	protein PRRC1 isoform 1
NM_130809.5	NP_570721.1	protein PRRC1 isoform 2

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	25416956	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PRRC1 Protein Structure

NTPase_I-T

0
100
200
300
400
445 a.a.

Protein Preferred Names

Protein Names

protein PRRC1

proline-rich and coiled-coil-containing protein 1

PRRC1 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	PRRC1	Q96M27	PIN1	Homo sapiens	Q13526	Y2H Prey Pooling	25416956
Intra	PRRC1	Q96M27	SEC23B	Homo sapiens	Q15437	Y2H Array	25416956
Intra	PRRC1	Q96M27	SEC23B	Homo sapiens	Q15437	Y2H Prey Pooling	25416956

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Dystonia 23

DYT23	Adult-Onset Cervical Dystonia, Dyt23 Type
Dystonia, Type 23

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11235	PRRC1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	PRRC1	VGNC	VGNC:64389
Rattus norvegicus	PRRC1	RGD	RGD:1565632
Mus musculus	PRRC1	MGD	MGI:1916106
Macaca mulatta	PRRC1	VGNC	VGNC:76329
Canis familiaris	PRRC1	VGNC	VGNC:45051
Bos taurus	PRRC1	VGNC	VGNC:33403

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