1. Gene
  2. Dnase1l3 - deoxyribonuclease 1-like 3 Gene

Dnase1l3 - deoxyribonuclease 1-like 3 Gene

Mus musculus

Also known as Lsd; Dhp2; DNasegamma

Gene ID: 13421 | Gene type: protein coding

About Dnase1l3

Summary

Enables Endonuclease activity. Involved in several processes, including DNA catabolic process, endonucleolytic; neutrophil activation involved in immune response; and regulation of neutrophil mediated cytotoxicity. Acts upstream of or within apoptotic DNA fragmentation and programmed cell death involved in cell development. Located in nucleus. Orthologous to human DNASE1L3 (deoxyribonuclease 1 like 3). [provided by Alliance of Genome Resources, Apr 2022]

Dnase1l3 Products(1)

mRNA Protein Name
NM_007870.3 NP_031896.3 deoxyribonuclease gamma precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables endonuclease activity IDA
IDA: Inferred from direct assay
12050166 MGI
Biological Process GO Annotation Evidence Reference Source
involved in DNA catabolic process IDA
IDA: Inferred from direct assay
29191910 MGI
acts upstream of or within apoptotic DNA fragmentation IDA
IDA: Inferred from direct assay
12050166 MGI
involved in neutrophil activation involved in immune response IDA
IDA: Inferred from direct assay
29191910 MGI
acts upstream of or within programmed cell death involved in cell development IDA
IDA: Inferred from direct assay
12050166 MGI
involved in regulation of acute inflammatory response IDA
IDA: Inferred from direct assay
29191910 MGI
involved in regulation of neutrophil mediated cytotoxicity IDA
IDA: Inferred from direct assay
29191910 MGI
Cellular Component GO Annotation Evidence Reference Source
located in nucleus IDA
IDA: Inferred from direct assay
12050166 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

deoxyribonuclease gamma

DNase I homolog protein DHP2

DNase I-like 3

DNase gamma

LS-DNase

deoxyribonuclease I-like 3

liver and spleen DNase

macrophage specific DNase I

Recombinant Dnase1l3 Proteins

Cat. No. Product Name Accession Purity
HY-P790035 DNase1L3 Protein, Mouse (His) O55070 (L26-S310) ≥95%

Orthologs Information

Species Symbol Source ID
Homo sapiens Dnase1l3 NCBI NCBI:1776