1. Gene
  2. CR1L - complement C3b/C4b receptor 1 like Gene

CR1L - complement C3b/C4b receptor 1 like Gene

Homo sapiens
Gene ID: 1379 | Gene type: protein coding

About CR1L

Cytogenetic location: 1q32.2 Genomic coordinates (GRCh38): 1:207,645,133-207,723,703 (from NCBI)

This gene has 5 transcripts (splice variants), 21 orthologues and 39 paralogues. Biased expression in bone marrow (RPKM 3.2), appendix (RPKM 1.6) and 5 other tissues.

Summary

Acts upstream of or within regulation of complement activation and regulation of complement-dependent cytotoxicity. Part of receptor complex. [provided by Alliance of Genome Resources, Apr 2022]

CR1L Products(1)

mRNA Protein Name
NM_175710.2 NP_783641.1 complement component receptor 1-like protein precursor

CR1L Protein Structure

Sushi

Sushi: Sushi repeat (SCR repeat) (35 - 91)

Sushi

Sushi: Sushi repeat (SCR repeat) (96 - 153)

Sushi

Sushi: Sushi repeat (SCR repeat) (158 - 224)

Sushi

Sushi: Sushi repeat (SCR repeat) (230 - 285)

Sushi

Sushi: Sushi repeat (SCR repeat) (289 - 345)

Sushi

Sushi: Sushi repeat (SCR repeat) (366 - 408)

Sushi

Sushi: Sushi repeat (SCR repeat) (413 - 470)

Sushi

Sushi: Sushi repeat (SCR repeat) (475 - 541)

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  • 569 a.a.
Protein Preferred Names Protein Names

complement component receptor 1-like protein

complement C4b-binding protein CR-1-like protein

Related Diseases

Diseases Alias
Complement Component Receptor 1
Cortisone Reductase Deficiency

11-Alpha Beta-Hydroxysteroid Dehydrogenase Type I Deficiency Of

Cortrd

Hsd 11b1 Deficiency

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Rattus norvegicus CR1L RGD RGD:2399
Mus musculus CR1L MGD MGI:88513