2. Gene
  3. F7 - coagulation factor VII Gene

F7 - coagulation factor VII Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Cf7; FVII

Gene ID: 14068 | Gene type: protein coding

About F7

Summary

This gene encodes a vitamin K-dependent serine protease that plays a critical role in the extrinsic pathway of blood coagulation. Upon contact with tissue factor III (TF III), the encoded protein forms an activated complex termed TF-FVIIa that initiates the coagulation cascade involving Other coagulation factors, ultimately resulting in a fibrin clot. Complete lack of the encoded protein in mice results in in perinatal lethality due to bleeding from normal blood vessels. [provided by RefSeq, Apr 2015]

F7 Products(1)

mRNA Protein Name
NM_010172.5 NP_034302.2 coagulation factor VII preproprotein
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within blood coagulation IMP
IMP: Inferred from mutant phenotype
9384381 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

coagulation factor VII

serum prothrombin conversion accelerator

Recombinant F7 Proteins

Cat. No. Product Name Accession Purity
HY-P73045 Coagulation Factor VII/F7 Protein, Mouse (CHO, His) Q542C2 (V25-L446) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (11)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-113437A 1,2-Dipalmitoyl-sn-glycerol 3-phosphate sodium ≥98.0% Unkown
HY-W250541 Fmoc-Gly-NH-CH2-O-Cyclopropane-CH2COOH 96.03% Unkown
HY-122678 LQZ-7F 97.13% Unkown
HY-113437AS 1,2-Dipalmitoyl-sn-glycerol 3-phosphate-d62 sodium ≥99.0% Unkown
HY-113437 1,2-Dipalmitoyl-sn-glycerol 3-phosphate / Unkown
HY-146033 HPV18-IN-1 Inhibitor / Unkown
HY-148696A Gly-Cyclopropane-Exatecan Inhibitor / Unkown
HY-156095 F7H Inhibitor 99.42% Unkown
HY-RS04116 E2F7 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS04645 F7 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-46572 Benzyl 2-cyclopropyl-2-hydroxyacetate 98.43% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens F7 NCBI NCBI:2155
Macaca fascicularis F7 NCBI NCBI:102121077
Rattus norvegicus F7 NCBI NCBI:260320
Macaca mulatta F7 NCBI NCBI:721933