Gpr6 - G protein-coupled receptor 6 Gene

Mus musculus

Also known as Gm233

Gene ID: 140741 | Gene type: protein coding

About Gpr6

Chromosome 10: 40,945,973-40,948,281 reverse strand.GRCm39:CM001003.3

This gene has 1 transcript (splice variant), 186 orthologues, 18 paralogues and is associated with 3 phenotypes. Biased expression in cortex adult (RPKM 1.6), CNS E18 (RPKM 1.2) and 7 other tissues.

Summary

Enables sphingosine-1-phosphate receptor activity. Acts upstream of or within positive regulation of cytosolic calcium ion concentration. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in cytoplasm and plasma membrane. Is expressed in several structures, including alimentary system; eye; immune system; male reproductive gland or organ; and nervous system. Orthologous to human GPR6 (G protein-coupled receptor 6). [provided by Alliance of Genome Resources, Apr 2022]

Gpr6 Products(1)

mRNA	Protein	Name
NM_199058.2	NP_951013.1	G-protein coupled receptor 6

Gpr6 Protein Structure

7tm_GPCRs

0
100
200
300
363 a.a.

Protein Preferred Names

Protein Names

G-protein coupled receptor 6

sphingosine 1-phosphate receptor GPR6

Related Agents

Clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-134661A	CVN424		99.70%	Phase 2

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-134661	(S)-CVN424		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Gpr6	NCBI	NCBI:2830

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