2. Gene
  3. Il2rg - interleukin 2 receptor subunit gamma Gene

Il2rg - interleukin 2 receptor subunit gamma Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Cd132; Ab2-183

Gene ID: 140924 | Gene type: protein coding

About Il2rg

Summary

Predicted to enable interleukin-15 receptor activity and interleukin-2 binding activity. Predicted to be involved in interleukin-15-mediated signaling pathway and positive regulation of phagocytosis. Predicted to act upstream of or within positive regulation of gene expression and positive regulation of lymphocyte differentiation. Predicted to be located in cell surface. Predicted to be part of receptor complex. Predicted to be active in external side of plasma membrane. Used to study X-linked severe combined immunodeficiency and combined T cell and B cell immunodeficiency. Human ortholog(s) of this gene implicated in X-linked severe combined immunodeficiency; combined T cell and B cell immunodeficiency; and severe combined immunodeficiency. Orthologous to human IL2RG (interleukin 2 receptor subunit gamma). [provided by Alliance of Genome Resources, Apr 2022]

Il2rg Products(1)

mRNA Protein Name
NM_080889.1 NP_543165.1 cytokine receptor common subunit gamma precursor
Protein Preferred Names Protein Names

cytokine receptor common subunit gamma

interleukin 2 receptor, gamma (severe combined immunodeficiency)

Recombinant Il2rg Proteins

Cat. No. Product Name Accession Purity
HY-P74805 IL-2R gamma/CD132 Protein, Rat (HEK293, His) Q68FU6 (S25-A262) ≥95%
HY-P74806 IL-2R gamma/CD132 Protein, Rat (HEK293, hFc) Q68FU6 (S25-A262) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06750 IL2RG Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Il2rg NCBI NCBI:3561
Macaca fascicularis Il2rg NCBI NCBI:102144912
Mus musculus Il2rg NCBI NCBI:16186