Fgf7 - fibroblast growth factor 7 Gene

Mus musculus

Also known as Kgf; Fgf5b

Gene ID: 14178 | Gene type: protein coding

About Fgf7

Summary

Predicted to enable heparin binding activity; receptor ligand activity; and type 2 Fibroblast Growth Factor receptor binding activity. Involved in positive regulation of transcription, DNA-templated. Acts upstream of or within morphogenesis of an epithelium; positive regulation of epithelial cell proliferation; and regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling. Located in Golgi apparatus and extracellular region. Is expressed in several structures, including alimentary system; brain; embryo mesenchyme; genitourinary system; and integumental system. Orthologous to human FGF7 (Fibroblast Growth Factor 7). [provided by Alliance of Genome Resources, Apr 2022]

Fgf7 Products(1)

mRNA	Protein	Name
NM_008008.4	NP_032034.1	fibroblast growth factor 7 precursor

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	15806171	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within branching involved in salivary gland morphogenesis	IDA IDA: Inferred from direct assay	18559345	MGI
acts upstream of endothelial cell proliferation	IDA IDA: Inferred from direct assay	14697353	MGI
acts upstream of epithelial cell proliferation	IDA IDA: Inferred from direct assay	17187775	MGI
acts upstream of or within hair follicle morphogenesis	IMP IMP: Inferred from mutant phenotype	11098134	MGI
acts upstream of myoblast proliferation	IDA IDA: Inferred from direct assay	15806171	MGI
acts upstream of myoblast proliferation	IGI IGI: Inferred from genetic interaction	15806171	MGI
involved in positive regulation of DNA-templated transcription	IDA IDA: Inferred from direct assay	17394208	MGI
acts upstream of or within positive regulation of endothelial cell proliferation	IDA IDA: Inferred from direct assay	14697353	MGI
acts upstream of or within positive regulation of epithelial cell proliferation	IDA IDA: Inferred from direct assay	17187775	MGI
acts upstream of or within positive regulation of myoblast proliferation	IDA IDA: Inferred from direct assay	15806171	MGI
acts upstream of or within positive regulation of myoblast proliferation	IGI IGI: Inferred from genetic interaction	15806171	MGI
acts upstream of or within regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling	IDA IDA: Inferred from direct assay	18559345	MGI
involved in regulation of synapse maturation	IDA IDA: Inferred from direct assay	20505669	MGI
involved in regulation of synapse maturation	IMP IMP: Inferred from mutant phenotype	20505669	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
is active in GABA-ergic synapse	IDA IDA: Inferred from direct assay	20505669	MGI
is active in GABA-ergic synapse	IMP IMP: Inferred from mutant phenotype	20505669	MGI
located in Golgi apparatus	IDA IDA: Inferred from direct assay	12837279	MGI
located in extracellular region	IDA IDA: Inferred from direct assay	12837279	MGI
is active in postsynapse	IDA IDA: Inferred from direct assay	20505669	MGI
is active in postsynapse	IMP IMP: Inferred from mutant phenotype	20505669	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

fibroblast growth factor 7

FGF-7	HBGF-7
Keratinocyte growth factor	fibroblast growth factor 5b
heparin-binding growth factor 7

Recombinant Fgf7 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P7176	KGF/FGF-7 Protein, Mouse	P36363 (C32-T194)	≥95%

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04905	FGF7 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Fgf7	NCBI	NCBI:2252

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