2. Gene
  3. Vegfd - vascular endothelial growth factor D Gene

Vegfd - vascular endothelial growth factor D Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Figf; VEGF-D

Gene ID: 14205 | Gene type: protein coding

About Vegfd

Summary

This gene encodes a member of the vascular endothelial growth factor (VEGF) family that acts as a ligand for vascular endothelial growth factor receptor 3. Signalling through this protein is important for growth and development of endothelial and vascular tissue. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015]

Vegfd Products(6)

mRNA Protein Name
NM_001308489.2 NP_001295418.1 vascular endothelial growth factor D isoform VEGF-D326 preproprotein
NM_001410630.1 NP_001397559.1 vascular endothelial growth factor D isoform VEGF-D326 preproprotein
NM_001410631.1 NP_001397560.1 vascular endothelial growth factor D isoform 3 precursor
NM_001410632.1 NP_001397561.1 vascular endothelial growth factor D isoform 4
NM_001410633.1 NP_001397562.1 vascular endothelial growth factor D isoform 5
NM_010216.3 NP_034346.1 vascular endothelial growth factor D isoform VEGF-D358 preproprotein
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables growth factor activity IDA
IDA: Inferred from direct assay
8876195 MGI
enables identical protein binding IPI
IPI: Inferred from physical interaction
11279005 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
11279005 MGI
enables vascular endothelial growth factor receptor 3 binding IDA
IDA: Inferred from direct assay
11279005 MGI
Biological Process GO Annotation Evidence Reference Source
involved in dopaminergic neuron differentiation IDA
IDA: Inferred from direct assay
22535492 MGI
acts upstream of or within fibroblast proliferation IDA
IDA: Inferred from direct assay
8876195 MGI
acts upstream of or within response to bacterium IEP
IEP: Inferred from expression pattern
23012479 MGI
acts upstream of or within vascular endothelial growth factor receptor signaling pathway IGI
IGI: Inferred from genetic interaction
11574540 MGI
Cellular Component GO Annotation Evidence Reference Source
located in extracellular region IDA
IDA: Inferred from direct assay
8876195 MGI
located in extracellular space IDA
IDA: Inferred from direct assay
11574540 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

vascular endothelial growth factor D

c-fos induced growth factor

Recombinant Vegfd Proteins

Cat. No. Product Name Accession Purity
HY-P72430 VEGF-DD Protein, Mouse (HEK293, His) P97946 (F98-S206) ≥95%
HY-P73474 VEGF-DD Protein, Mouse (HEK293, Fc) P97946 (F98-S206) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15638 VEGFD Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P9920A Ramucirumab (anti-VEGFR) Antagonist 99.36% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Vegfd NCBI NCBI:2277